Comparison of Piperine, Vitamin E, and Piperine with Vitamin E Oral Capsules Effects on Premenstrual Syndrome

Phase 1

• Conditions: Premenstrual syndrome (PMS).; Premenstrual tension syndrome

• Registration Number: IRCT201508022172N19
• Lead Sponsor: Vice chancellor for research and technology, Iran University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 February 2018

Recruitment & Eligibility

• Status: Complete
• Sex: Female
• Target Recruitment: 180

Inclusion Criteria

age between 18 and 35 years old; being single; being healthy regarding to their self-report and physical examination; having regular menstrual cycles (22-35 days and 2-7 days duration); having premenstrual syndrome (PMS) in 2 past cycles (no sever syndrome); no history of allergy to any food; not taking any medicine; not taking any complements; not smoking, alcohol or drug usage; no history of pregnancy. Exclusion criteria: use of any kind of drug or therapy for symptom relief during the study intervention; side effects during intervention for example allergy; change in diet or physical exercise program during the study; any kind of crisis in participant or her family; not taking capsules more than 7 days in 2 cycles

Exclusion Criteria

Not provided

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Premenstrual syndrome (screening). Timepoint: 2 menstrual cycles. Method of measurement: premenstrual profile 2005 scale.

Secondary Outcome Measures

Name	Time	Method
Premenstrual syndrome (prevention). Timepoint: During intervention for 2 cycles. Method of measurement: Measure by premenstrual profile 2005 scale, for duration of 2 cycles.