Evaluation of the Effect of Silymarin, an Antioxidant, on Oxidative Stress Markers in Hemodialysis Patients
Phase 3
- Conditions
- End Stage Renal Disease.End-stage renal disease
- Registration Number
- IRCT138904234376N1
- Lead Sponsor
- Mohammad Hossein Dabaghmanesh
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 80
Inclusion Criteria
Clinically stable patients within the age range of 18-60.
Undergoing maintenance hemodialysis initiated >=3 months previously at a rate of 3 times per week, each session 4 hours.
Exclusion criteria: History of cardiovascular event within the previous 12 months, use of cholestrol-lowering agents(statins), Omega-3, Vitamin E, Levothyroxin, and oral contraceptive pills (OCP), infections including HBV, HCV, heart failure class III and IV according to New York Heart Association(NYHA) were also excluded.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Hemoglobin level. Timepoint: 21 days. Method of measurement: Sampling and Biochemical Analysis.;Oxidative Stress Markers level. Timepoint: 21 days. Method of measurement: Sampling and Biochemical Analysis.
- Secondary Outcome Measures
Name Time Method