CTRI/2024/06/069683尚未招募不适用
Comparative Evaluation of Sugammadex Versus Neostigmine on Recovery of Respiratory Muscle Strength in the Post Extubation Period.
ESIC Medical College and Hospital1 个研究点 分布在 1 个国家目标入组 60 人开始时间: 2024年7月15日最近更新:
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- To evaluate and compare the effect of sugammadex and neostigmine on difference in thickening fraction of internal oblique (TFIO) from baseline to TOFR more than or equal to 0.9
研究概览
简要总结
i will do this study to compare the effect of sugammadex versus neostigmine on recovery of respiratory muscle strength by measuring thickening fraction of internal oblique muscle and diaphragm excursion at three point times preoperatively, post extubating and 30 minutes after shifted to PACU. My research question is whether sugammadex will enhance expiratory muscle strength recovery more than neostigmine in the immediate post extubating period.
研究设计
- 研究类型
- Interventional
- 分配方式
- Other
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 65.00 Year(s)（—）
- 性别
- All
入选标准
- •American Society of Anaesthesiologist (ASA) physical status 1 and 2 posted for surgery under general anaesthesia.
排除标准
- •Parturient or lactating women OR undergoing thoracic or abdominal surgery OR neuromuscular disease chronic obstructive pulmonary disease significant kidney and liver disease OR allergic to rocuronium neostigmine.
结局指标
主要结局
To evaluate and compare the effect of sugammadex and neostigmine on difference in thickening fraction of internal oblique (TFIO) from baseline to TOFR more than or equal to 0.9
时间窗: preoperative and in Post extubation at TOFR more than or equal to 0.9
次要结局
- compare change in TFIO and diaphragm excursion from baseline to 30 minutes in PACU in both groups(30 minutes in PACU)
研究者
DR Sonia Saini
ESIC Medical College and Hospital
研究点 (1)
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