Study of the Natural Variation in Strokevolume

Completed

• Conditions: Stroke Volume Variation

• Registration Number: NCT00447200
• Lead Sponsor: Rigshospitalet, Denmark

Brief Summary

We would like to investigate the natural variation in the strokevolume of the heart. At the same time we would like to find out the minimal number of heart cycles necessary to discover a 10% increase in strokevolume, after a fluid bolus of 200ml Voluven, when using Esophageal Doppler.

Detailed Description

We would like to investigate the natural variation in the strokevolume(SV) of the heart. At the same time we would like to find out the minimal number of heart cycles necessary to discover a 10% increase in SV, after a fluid bolus of 200ml Voluven, when using Esophageal Doppler.

Also we will compare the variation in SV both before and after the patients have been fluid optimized, using an algorithm of 10% increase in SV in order to receive another fluid bolus. The equipment used, will be the CardioQ from Deltex medical.

Study Timeline

• Study Start: 2007-03
• Study First Submitted: 2007-03-13
• Study First Submitted QC: 2007-03-13
• Study First Posted: 2007-03-14
• Study Completion: 2007-08
• Status Verified: 2007-10
• Last Update Submitted: 2007-10-12
• Last Update Posted: 2007-10-15

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

• Planned abdominal surgery

Exclusion Criteria

• Oesophageal pathology,
• Age >90 yr or <18 yr,
• Alcohol abuse,
• Aneurism in thoracic aorta

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Strokevolume variation before fluid optimization
Strokevolume variation after fluid optimization
Number of cycles needed in order to detect a 10% strokevolume increase after fluid bolus of 200ml Voluven.

Trial Locations

Locations (1)

Rigshospitalet; 🇩🇰 Copenhagen, Seeland, Denmark