Procedure and In-hospital Outcome of Patients Under 40 Years Old Undergoing Primary Percutaneous Coronary Intervention for Acute ST Elevated Myocardial Infarction in Assiut University
试验速览
- 阶段
- 不适用
- 入组人数
- 117
- 试验地点
- 1
- 主要终点
- clinical outcome
研究概览
简要总结
Sample size of 117 patients presented with ST elevated myocardial infarction for PPCI starting from september 2017 will be divided to 2 groups, group 1 age up to 40 years old and group 2 older than 40 years then previous history and clinical data and angiographic data at PPCI and follow up in-hospital and after discharge for 3 months all these data will be compared at both groups.
详细描述
Myocardial infarction (MI) is a disease of middle and advanced age.
Most of the present knowledge of infarction is derived from studies in this older cohort of patients.
In fact, some clinical studies of patients with chest pain have excluded individuals under 40 years of age
Although thrombolytic therapy has been shown to improve survival in elderly AMI patients when compared with placebo, many studies have shown lower mortality rates when these patients are treated with primary percutaneous coronary intervention(PPCI) for AMI
Young adults are a relatively small portion of those having acute myocardial infarction (AMI). However they are an important group to examine with regard to risk factor modification and secondary prevention.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •All patients with acute myocardial infarction (STEMI): chest pain > 30 minutes and ST segment elevation in more than one lead, treated with PPCI at Assiut University Hospitals starting from September 2017.
排除标准
- •Patients undergoing elective percutaneous intervention and thrombolytic therapy.
结局指标
主要结局
clinical outcome
时间窗: 48 hours
Evaluation of PCI success (in-hospital): 1. angiographic success: (residual stenosis ≤ 30% and TIMI flow grade 3) and side branch angiographic success (residual stenosis ≤ 50% and TIMI flow grade 3) am 2. procedural success: achievement of angiographic success without major clinical complication as (death, MI,emergency coronary artery bypass surgery) during hospitalization. 3. clinical success: in the short term, recovering of signs and symptoms of myocardial ischemia.
次要结局
未报告次要终点
研究者
mohamed taha galal
resident at cardiology department at assiut university hospital
Assiut University