Antibiotica voor de behandeling van acute blindedarmontsteking bij kinderen.
Completed
- Conditions
- AppendicitischildrenAntibiotic treatmentNon-operative treatment
- Registration Number
- NL-OMON26391
- Lead Sponsor
- VU University Medical Center
- Brief Summary
/A
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 50
Inclusion Criteria
• Age 7-17 years
• Radiologically confirmed simple appendicitis, defined as:
Exclusion Criteria
1. Patients with severe general illness at time of presentation:
a. Generalized peritonitis defined as:
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Safety of initial antibiotic treatment defined as:<br /><br>Occurrence of major complications, such as:<br /><br>A. Anaphylactic shock and other allergic reaction to antibiotics administered<br /><br> b. Recurrent appendicitis within 8 weeks<br /><br> c. Recurrent appendicitis within one year after discharge<br /><br> d. Development of perforated appendicitis<br /><br>e. Occurrence of major complaints after delayed appendectomy such as intra-abdominal abscess (IAA), stumpleakage, superficial site infection (SSI), anaesthesia related complications, secondary bowel obstruction (SBO), re-admission, need for re-intervention<br /><br>f. Re-admission<br /><br>g. Re-intervention other than delayed appendectomy
- Secondary Outcome Measures
Name Time Method Major complications associated with appendectomy <br /><br> a. Stumpleakage<br /><br> b. Intra-abdominal abscess (IAA)<br /><br> c. Secondary bowel obstruction (SBO)<br /><br> d. Superficial site infection (SSI)<br /><br> e. Need for secondary operation<br /><br> f. Need for other re-intervention<br /><br> g. Re-admission<br /><br> h. Anaesthesia related complication<br /><br> i. Pneumonia<br />