A Comprehensive Evaluation of Tobacco-Flavored vs. Non-Tobacco Flavored E-cigarettes on Smoking Behavior

Not Applicable

Recruiting

• Conditions: Cigarette Smoking-Related Carcinoma

• Registration Number: NCT06260683
• Lead Sponsor: Ohio State University Comprehensive Cancer Center

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2024-2-7
• Last Update Posted: 2 September 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 1500

Inclusion Criteria

Inclusion Criteria:<br><br> - >= 21 years old<br><br> - Smoke >= 5 cigarettes per day for the past year<br><br> - Willing to use either an EC or NRT<br><br> - Read and speak English<br><br> - Have a smartphone<br><br>Exclusion Criteria:<br><br> - Report currently using smoking cessation medications, NRT, or actively seeking<br> treatment for smoking cessation<br><br> - Current use of an EC > 4 days a month<br><br> - Diagnosed medical conditions of lung disease, asthma, cystic fibrosis, heart disease<br> or chronic obstructive pulmonary disease (COPD)<br><br> - Unmanaged (unmedicated and/or without counseling) diagnosis of schizophrenia<br><br> - History of cardiac event or distress within the past 3 months<br><br> - Currently pregnant, planning to become pregnant within 6 months, or breastfeeding<br><br> - High blood pressure not controlled by medications<br><br> - Serious angina pectoris or chest pain<br><br> - Stroke within the past three months<br><br> - Known allergy to propylene glycol or vegetable glycerin

Exclusion Criteria

Not provided

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Biochemically verified 7-day point prevalence abstinence from cigarettes;Switching rate

Secondary Outcome Measures

Name	Time	Method
Number of days used;Product appeal;Continued purchase and use of ECs;Cigarettes smoked per day;Change in nicotine dependence;Changes in cigarette craving and nicotine withdrawal