CANDIS-II: Evaluation of the Cognitive-behavioral Treatment Programme CANDIS

Phase 3

• Conditions: Cannabis Use Disorders
• Interventions: Behavioral: Cognitive-behavioral treatment

• Registration Number: NCT00673647
• Lead Sponsor: Technische Universität Dresden

Brief Summary

The purpose of this study is to evaluate the effectiveness of the cognitive-behavioral treatment program CANDIS among n=450 patients with cannabis use disorders in a mulicenter randomized-controlled clinical trial (n=11 outpatient treatment centers).

Detailed Description

Not available

Study Timeline

• Study Start: 2008-05
• Study First Submitted: 2008-05-01
• Study First Submitted QC: 2008-05-06
• Study First Posted: 2008-05-07
• Status Verified: 2009-08
• Last Update Submitted: 2009-08-25
• Last Update Posted: 2009-08-26
• Primary Completion: 2009-10
• Study Completion: 2009-10

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 450

Inclusion Criteria

• motivation to change cannabis use
• age 16 or older
• current (12 mth) regular cannabis use (at least 2 days a week)
• informed consent to the study procedures and assessments

Exclusion Criteria

• current alcohol or any illicit drug dependence syndrome according to DSM-IV other than due to cannabis
• lifetime history of any psychotic disorder
• current severe episode of Major depression
• current panic-agoraphobic disorder (severe)
• severe learning disability, brain damage or pervasive developmental disorder
• currently acute suicidality
• not fluent in german language
• any other current treatment for cannabis use disorders

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
1	Cognitive-behavioral treatment	Individual psychotherapy including cognitive behavioral components, motivational interviewing techniques and case management

Primary Outcome Measures

Name	Time	Method
abstinence, defined as no evidence of cannabis use during the past 4 weeks as evidenced by self report and a negative urine screen; number of times a cannabis product was used in the past 4 weeks; retention rate	at the end of treatment

Trial Locations

Locations (11)

Jugend- und Drogenberatung Dresden; 🇩🇪 Dresden, Germany

Caritas Fachambulanz für Suchtprävention und Rehabilitation Osnabrück; 🇩🇪 Osnabrueck, Germany

Release Stuttgart e.V. & Ambulante Beratungs- und Behandlungsstelle Klinikum Stuttgart; 🇩🇪 Stuttgart, Germany

LogIn Jugend- und Suchtberatung; 🇩🇪 Berlin, Germany

Jugend- und Drogenberatung Braunschweig; 🇩🇪 Braunschweig, Germany

Die Boje - Suchtberatung und Behandlung; 🇩🇪 Hamburg, Germany

Drobs Hannover; 🇩🇪 Hannover, Germany

Suchtambulanz der LWL-Klinik Münster; 🇩🇪 Muenster, Germany

Caritas-Fachambulanz für junge Suchtkranke; 🇩🇪 Muenchen, Germany

Psychosoziale Beratungs- und Behandlungsstelle für Suchtgefährdete und -kranke; 🇩🇪 Bautzen, Germany

Therapieladen e.V.; 🇩🇪 Berlin, Germany