Post Operative Pain Control Among Intrathecal 0.1 mg Morphine, Femoral Nerve Block, or Periarticular Infiltration of 20 mL of 0.25% Bupivacaine in Patients Post Intramedullary Hip Screw
试验速览
- 阶段
- 4 期
- 入组人数
- 80
- 试验地点
- 1
- 主要终点
- The amount of morphine consumption.
研究概览
简要总结
Falls are a common problem in elderly patients resulting fractured femur, which require early operation. Adequate postoperative pain control will provide good recovery. The investigators will compare the efficacy of postoperative pain control among intrathecal morphine, femoral nerve block, and periarticular infiltration with bupivacaine in patients undergone intramedullary hip screw under spinal anesthesia.
详细描述
Study methods :
Every patients without any exclusion criteria will be performed spinal anesthesia by 0.5% heavy bupivacaine then divided into 4 groups
- Controlled group : spinal anesthesia alone
- Femoral nerve block by 20 mL of 0.25% bupivacaine before spinal anesthesia
- Spinal anesthesia plus 0.1 mg morphine intrathecally
- Spinal anesthesia plus periarticular infiltration with 20 mL of 0.25% bupivacaine
All patients will receive postoperative intravenous patient controlled analgesia (IV PCA) morphine for 48 hours.
Data collection
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 90 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •18-90 years old
- •good consciousness, well co-operated, can use PCA machine
- •ASA class 1-3
- •no contraindication of spinal anesthesia
- •accept for spinal anesthesia
- •body weight > 30 kg
- •BMI 20-35 kg/m2
- •no history of research-drug allergy
排除标准
- •previous history of hip surgery (the same side)
- •pathological fractured such as severe infection, bone cancer
研究组 & 干预措施
Controlled group
Spinal anesthesia with 0.5% bupivacaine alone
干预措施: Bupivacaine, morphine (Drug)
Femoral nerve block
Spinal anesthesia plus femoral nerve block with 20 mL of 0.25% bupivacaine
干预措施: Bupivacaine, morphine (Drug)
Intrathecal morphine
Spinal anesthesia plus 0.1 mg of intrathecal morphine
干预措施: Bupivacaine, morphine (Drug)
Periarticular bupivacaine infiltration
Spinal anesthesia plus periarticular infiltration with 20 mL of 0.25% bupivacaine
干预措施: Bupivacaine, morphine (Drug)
结局指标
主要结局
The amount of morphine consumption.
时间窗: 24 hours postoperative
次要结局
- Efficacy of pain control(48 hours postoperative)