Mobile Oral Cancer Screening In Limited Resource Setting

Completed

Conditions: Leukoplakia and other disturbancesof oral epithelium, including tongue, (2) ICD-10 Condition: C00-C14||Malignant neoplasms of lip, oral cavity and pharynx,

Brief Summary: Thisproject is a multicentric study, in India at three sub-centers. The aim of this research is to empower the health care workers in ruralIndia to identify oral & pharyngeal lesions with a mobile phone. The deviceacts as â€œPoint of Careâ€ diagnosis for early detection of Oral Cancer andapproach creates an opportunity to connect specialists to rural population,facilitates timely referrals and follow up. Study aimed at Field validation of mobileintraoral system for Oral cancer in LMIC settings.

Recruitment & Eligibility

Inclusion Criteria

Clinically Suspicious oral Lesions (Including leukoplakia, erythroplakia, Lichen planus, benign lesions- epithelial tumors, ulcers, vesiculobullous lesions like pemphigus vulgaris) 2.
History of previously treated OSCC, with no current evidence of cancer recurrence at least for 6 months after cessation of treatment.
Presence of recently diagnosed untreated OSCC or a precancerous lesion 4.
Individuals positive for tobacco habit.

Exclusion Criteria

Primary Outcome Measures

Name	Time	Method
1. Identification of Oral precancer and cancer by Frontline healthcare providers using point of care diagnostic tool.	Interim analysis performed at the end of 12months to assess FHPs for identification of oral precancer and cancer using point of care diagnostic tool \| At the end of two and half years to develop AI based algorithm
2. To develop an AI based diagnosis	Interim analysis performed at the end of 12months to assess FHPs for identification of oral precancer and cancer using point of care diagnostic tool \| At the end of two and half years to develop AI based algorithm

Secondary Outcome Measures

Name	Time	Method
To evaluate the agreement between FHPs/ Onsite specialist/ Remote specialist/ AI algorithm	To evaluate the agreement between the remote diagnosis/ Biopsy

Locations (3): Christian Institute of Health Sciences and Research
🇮🇳
Dimapur, NAGALAND, India
KLE Societyâ€™s Institute of Dental Sciences
🇮🇳
Bangalore, KARNATAKA, India
Mazumdar Shaw Medical Center
🇮🇳
Bangalore, KARNATAKA, India
Christian Institute of Health Sciences and Research
🇮🇳Dimapur, NAGALAND, India
Dr Rohan Michael Ramesh
Principal investigator
917085055422
roan.ramesh@gmail.com