ISRCTN64847145
Completed
Not Applicable
Exploring the relationship between insulin resistance and interferon resistance: options to overcome Hepatitis C Virus (HCV) non-response to pegylated interferon
Imperial College London and Imperial College Healthcare NHS Trust (UK)0 sites22 target enrollmentJanuary 15, 2010
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Hepatitis C Virus (HCV) infection
- Sponsor
- Imperial College London and Imperial College Healthcare NHS Trust (UK)
- Enrollment
- 22
- Status
- Completed
- Last Updated
- 11 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •1\. Chronic HCV genotype 1 infection
- •2\. Chronic HCV and compensated liver cirrhosis who failed to respond to previous treatment
- •3\. Age \>17, \<70
- •4\. Eligible for interferon therapy
Exclusion Criteria
- •1\. HIV or HBV co\-infection
- •2\. Current use antidiabetic medication (e.g., insulin, metformin or thiazolidinedione)
- •3\. Significant respiratory, cardiac or renal dysfunction
- •4\. Body Mass Index \> 30 kg/m2
Outcomes
Primary Outcomes
Not specified
Similar Trials
Active, not recruiting
Phase 1
Exploring the Relationship Between Insulin Resistance and Interferon Resistance: Options to Overcome HCV Non-Response to Pegylated Interferon - The Relationship Between Insulin Resistance and Interferon resistanceEUCTR2009-016678-34-GBImperial College London22
Active, not recruiting
Phase 1
Effects of glucocorticoids on human gut bacteriaEUCTR2016-001850-16-DKniversity of Copenhagen, The Novo Nordisk Foundation Center For Basic Metabolic Research, Section of Metabolic Genetic
Completed
Not Applicable
Investigation for the relationship between insulin resistance and alcohol intake.diabetesJPRN-UMIN000009537Juntendo University Graduate School of Medicine10
Completed
Not Applicable
The analysis of effects on insulin resistance and atherosclerotic risk factors before and after the treatment in patients with primary aldosteronism (PA)Primary aldosteronismJPRN-UMIN000002196Faculty of Life Sciences, Kumamoto University20
Completed
Phase 4
Impact on insulin sensitivity and insulin resistance after the conversion from tacrolimus twice daily to extended-release tacrolimus once daily in stable renal transplant recipientsinsulin sensitivityinsulin resistanceinsulin sensitivityinsulin resistancetacrolimusextended release tacrolimus once dailyTCTR20151005001Prajej Ruangkanchanasetr28