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The efficacy and safety of oraCMU on oral health

Not Applicable
Recruiting
Conditions
Not Applicable
Registration Number
KCT0004291
Lead Sponsor
Seoul National University Dental Hospital
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
All
Target Recruitment
100
Inclusion Criteria

1) Those who voluntarily agree to participate in this study and sign in informed consent form
2) Men and women between 20 and 70 years old
3) Those who have 20 or more natural teeth excluding wisdom teeth
4) Those who without tongue diseases
5) A person with volatile sulfur compounds concentration of 1.5 ng/10 ml or more
6) Persons without severe periodontal disease, rampant caries, less than five dental caries to be treated immediately

Exclusion Criteria

1) Those who have communication problem with investigators
2) Those who have mental diseases
3) Those who are currently being treated with systemic disease that may cause bad breath
4) Those who have a diagnosis of sinusitis or rhinitis
5) Those taking antibiotics within 1 month before the first visit
6) Those who have a diagnosis of chronic gastritis
7) Those with uncontrolled hypertension
8) Diabetic patients taking hypoglycemic agents
9) Those who consume food or health functional food with probiotics within 1 week before the first visit
10) Those who have hypersensitivity or allergy to probiotics including dairy food
11) Those taking warfarin or aspirin
12) Those who have aspiration risk
13) Those who have dry mouth
14) Persons with severe periodontal disease, rampant caries, five or more dental caries to be treated immediately
15) Pregnant or lactating women, or with pregnancy plan during the study period
16) Those who have participated in other clinical trials within 6 months before participating in this study
17) Those who are deemed by the investigator to be unsuitable for this study

Study & Design

Study Type
Interventional Study
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Halitosis, gingival index, periodontal bacteria
Secondary Outcome Measures
NameTimeMethod
Psychosocial health survey;Blood test
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