Role of Bilateral Repetitive Transcranial Magnetic Stimulation in Stroke Patients
- Conditions
- Nervous System Diseases
- Registration Number
- PACTR201907882363035
- Lead Sponsor
- Dina Ahmed El Salmawy
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 55
-Patients presenting by their first ischemic or hemorrhagic cerebrovascular stroke within >two weeks from onset so patients could have passed the flaccid stage and < six months duration of symptoms, as the best cortical plasticity is obtained in a period less than six months(Takeuchi et al., 2009).
-Subcortical hemispheric stroke confirmed by magnetic resonance imaging (MRI).
-Patients of a minor (1-4) to moderate (5-15) national institutes of health stroke scale score (Lyden, Lu & Levine, 2001) to allow patient to receive treatment and perform tests (Wolf Motor function test and Fugl Meyer assessment) to assess improvement with minimum assistance.
-No prior experience of rTMS to confirm blindness of the intervention
-Family history of epilepsy or patients who are known to be epileptic.
-Pregnant females.
-Convulsion after the stroke onset
-Patients with any medical metal devices incompatible with transcranial magnetic stimulation (pacemaker).
-Bi-hemispheric or multifocal stroke.
-Premorbid lower motor neuron impairment prior to the onset of stroke like peripheral neuropathy or radiculopathy.Other comorbidities as fracture or deformity.
-Patients with heart failure
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Assesment Of bilateral rtms therapy (Stimulatory 5Hz rTMS over the affected hemisphere alternated by inhibitory 1Hz rTMS over the non-affected hemisphere) could lead to an improvement in the motor function of the paretic hand in stroke patients
- Secondary Outcome Measures
Name Time Method improvement of post stroke spascity if present