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Clinical Trials/NCT06731712
NCT06731712
Completed
N/A

Targeted Physical Function Exercises on Frailty and Falls Management in Pre-Frail Community-Dwelling Older Adults: a Randomized Controlled Trial

Hellenic Mediterranean University1 site in 1 country121 target enrollmentDecember 15, 2022

Overview

Phase
N/A
Intervention
Not specified
Conditions
Frailty Syndrome
Sponsor
Hellenic Mediterranean University
Enrollment
121
Locations
1
Primary Endpoint
Level of Frailty status
Status
Completed
Last Updated
last year

Overview

Brief Summary

The investigators will conduct a randomized controlled trial to assess the impact of targeted physical function exercises on frailty and falls in community-dwelling adults over 65 years of age. Participants will be randomized to an intervention and a control group to undergo an 18-month assessment.

The hypothesis of this study is to investigate the impact of targeted physical function exercises on managing frailty status and concerns about falling among pre-frail older adults. By implementing individualized intervention programs tailored to improve strength, balance, and mobility, the investigators aim to enhance physical function and reduce the risk of frailty-related adverse health outcomes. The investigators seek to empower pre-frail older adults to proactively manage their health, maintain independence, and improve their quality of life as they age.

Registry
clinicaltrials.gov
Start Date
December 15, 2022
End Date
June 15, 2024
Last Updated
last year
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Hellenic Mediterranean University
Responsible Party
Principal Investigator
Principal Investigator

Konstantinos Giakoumidakis

Associate Professor

Hellenic Mediterranean University

Eligibility Criteria

Inclusion Criteria

  • participants aged 65 and over
  • classified as pre-frail according to SHARE-Frailty Instrument
  • independent of movement and activity
  • able to perform Mini-Mental Status Examination (MMSE) score ≥24

Exclusion Criteria

  • severe contraindications for physical exercise
  • central nervous system impairments
  • inability to speak and understand Greek properly
  • a cognitive state that prevents understanding the researcher's instructions

Outcomes

Primary Outcomes

Level of Frailty status

Time Frame: From baseline (T0), at 6 months (T1), at 12 months (T2), to the end of the intervention at 18 months (T3).

SHARE Frailty Instrument will be used. Diagnostic criteria include involuntary loss of weight and muscle mass, exhaustion, low physical activity, slowness, and reduced grip strength. The presence of three or more criteria indicates frailty, while the presence of less than three pre-frailty

Concerns about Falling

Time Frame: From baseline (T0), at 6 months (T1), at 12 months (T2), to the end of the intervention at 18 months (T3).

The Falls Efficacy Scale - International (FES-I), a 16-item questionnaire that assesses the participant's fall efficacy, will be used to measure the level of concern about falling during various social and physical activities. Every item has a four-point (1-4) score, summarizing a total score of 64 points. A 16-22 score indicates low concern about falling, and a 23-64 high concern.

Secondary Outcomes

  • Physical Performance(From baseline (T0), at 6 months (T1), at 12 months (T2), to the end of the intervention at 18 months (T3).)
  • Functional Mobility(From baseline (T0), at 6 months (T1), at 12 months (T2), to the end of the intervention at 18 months (T3).)
  • Functional Balance(From baseline (T0), at 6 months (T1), at 12 months (T2), to the end of the intervention at 18 months (T3).)
  • Quality of Daily Living(From baseline (T0), at 6 months (T1), at 12 months (T2), to the end of the intervention at 18 months (T3).)
  • Depression(From baseline (T0), at 6 months (T1), at 12 months (T2), to the end of the intervention at 18 months (T3).)

Study Sites (1)

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