The Effect of Different Local Anesthetic Volumes on Postoperative Analgesia for Thoracotomy Patients With Erector Spinae Plane Block

Not Applicable

Completed

• Conditions: Erector Spinae Plane Block; Thoracotomy; Postoperative Analgesia; Local Anesthetic
• Interventions: Procedure: Same blocks with different local anesthetic volume

• Registration Number: NCT05083845
• Lead Sponsor: Atatürk Chest Diseases and Chest Surgery Training and Research Hospital

Brief Summary

It is widely accepted that thoracotomy causes severe acute pain. This increases the frequency of postoperative pulmonary complications and postoperative morbidity. Many analgesic methods have been proposed for thoracotomy pain, including thoracic epidural analgesia (TEA), thoracic paravertebral block (TPVB), intercostal nerve blocks (ICSB), erector spinae plane block (ESPB), serratus anterior plane block (SAPB). Among these methods, ultrasound-guided TPVB and ESPB are the most used methods. TPVB has left its place to newer techniques such as ESPB due to its proximity to the pleura and its deeper location. ESPB is more superficial, easy to access, and less likely to have complications. In addition, ESPB application is increasing in patients who underwent thoracotomy and VATS. There is no consensus on the dose of analgesia in these studies. There are studies on volumes between 10 ml and 40 ml in the literature. In this study, it was aimed to compare the volumes of 20 ml and 30 ml containing local anesthetic at the same concentration (0.25% bupivacaine) of ESPB block to be performed with USG in patients who underwent thoracotomy.

Detailed Description

Not available

Study Timeline

• Study Start: 2021-08-25
• Study First Submitted: 2021-10-04
• Study First Submitted QC: 2021-10-06
• Study First Posted: 2021-10-19
• Primary Completion: 2022-06-09
• Status Verified: 2022-07
• Last Update Submitted: 2022-07-08
• Study Completion: 2022-07-09
• Last Update Posted: 2022-07-12

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• 18 to 65 years old
• ASA physical status I-II-III
• BMI 18 to 30 kg/m2
• Elective thoracotomy surgery

Exclusion Criteria

• Patient refusing the procedure
• Emergency surgery
• History of chronic opioid or analgesic used

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Erector Spinae Plane Block with 20 ml %0.25 Bupivacaine	Same blocks with different local anesthetic volume	Following the visualization of the anatomical structures, the nerve block needle was advanced via the in-plane technique beneath the erector spinae muscles until the interfascial space was reached. After hydrodissection with 2 ml normal saline, 20 ml 0.25% bupivacaine was injected into the area.
Erector Spinae Plane Block with 30 ml %0.25 Bupivacaine	Same blocks with different local anesthetic volume	Following the visualization of the anatomical structures, the nerve block needle was advanced via the in-plane technique beneath the erector spinae muscles until the interfascial space was reached. After hydrodissection with 2 ml normal saline, 30 ml 0.25% bupivacaine was injected into the area.

Primary Outcome Measures

Name	Time	Method
Pain Scores	48 hours after surgery	Pain will be assessed at rest and while coughing using the visual analog scale on a scale from 0 (no pain) to 10 (worst pain). Pain assessment will be done at 1st, 2nd, 4th, 8th, 16th, 24th and 48th hours after surgery.

Secondary Outcome Measures

Name	Time	Method
Morphine Consumption	24 hours after surgery	Morphine consumption for 24 hours will be recorded

Trial Locations

Locations (1)

Ankara Atatürk Chest Disease and Chest Surgery Training and Research Hospital; 🇹🇷 Kecioren, Ankara, Turkey