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To determine the kidney function in patients before and after enhanced external counterpulsation treatment

Completed
Conditions
Ischaemic heart disease, chronic stable angina, chronic stable heart failure
Circulatory System
Registration Number
ISRCTN11560035
Lead Sponsor
Piyavate Hospital (Thailand)
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
All
Target Recruitment
26
Inclusion Criteria

1. Both males and females, age >18 years
2. Patients with refractory angina, chronic stable angina or chronic stable heart failure
3. Willing to participate in the study with informed consent

Exclusion Criteria

1. Patient with the diagnosis of congestive heart failure within 1 month prior to study entry
2. Patient with the diagnosis of acute coronary syndrome within 1 month prior to study entry
3. Patient with uncontrolled blood pressure (>180/110 mmHg)
4. Patient with cardiac arrhythmia (e.g. atrial fibrillation or atrial flutter or frequent premature ventricular contractions) that may interfere with triggering of EECP system
5. Patients with severe lower extremity vaso-occlusive disease
6. Patients with end stage renal disease requiring renal replacement therapy

Study & Design

Study Type
Observational
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Serum cystatin C<br><br>All primary and secondary outcome measures will be assessed before and within 1 month, and 5-7 months after completion of EECP treatment of 35 sessions.
Secondary Outcome Measures
NameTimeMethod
1. Calculated glomerular filtration rate (GFR) <br>2. Serum N-Terminal pro-B-type Natriuretic Peptide (NT-proBNP) <br>3. Ejection fraction determined by echocardiography <br><br>All primary and secondary outcome measures will be assessed before and within 1 month, and 5-7 months after completion of EECP treatment of 35 sessions.
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