跳至主要内容
临床试验/NCT06620601
NCT06620601招募中不适用

Diagnosis and Treatment of Sleep Apnea in Shelter Residents

University Health Network, Toronto4 个研究点 分布在 1 个国家目标入组 100 人开始时间: 2021年10月20日最近更新:
适应症

试验速览

阶段
不适用
状态
招募中
入组人数
100
试验地点
4
主要终点
To assess the prevalence of sleep apnea in shelter residents.

研究概览

简要总结

In Canada, 35,000 people are experiencing homelessness on any night. Compared to the general population, people experiencing homelessness (PEH) sleep less and experience increased daytime fatigue. A common sleep disorder and treatable cause of morbidity and low quality of life is sleep apnea. High prevalence of chronic comorbid disorders of sleep apnea in PEH suggest high prevalence of sleep apnea, but the rate of sleep apnea treatment in PEH is very low. Also, in PEH, individual and systemic barriers lead to a high rate of underdiagnosed and untreated sleep apnea. Mortality is higher in PEH than the general population, and sleep apnea remains a potential silent cause of morbidity and low quality of life in PEH. Our goal is to diagnose and treat sleep apnea in people living in shelters and to examine the effect of patient-centered treatment on their quality of life.

详细描述

Background:

Disadvantaged individuals, including people experiencing homelessness, are at higher risk of getting infected, transmitting disease, and having poor health outcomes. Access to medical care, even within a system of universal health insurance like that of Canada, is decreased among people experiencing homelessness, but available evidence has demonstrated the efficacy of using telemedicine to reach vulnerable people in remote areas or people experiencing homelessness. However, at present, telemedicine-facilitated care in Canada is predominantly devoid of any technology to evaluate patient vital signals. The application of such technology to this population, if feasible, could have transformational implications for monitoring and management of such disadvantaged populations. Currently, it is known that there is a greater prevalence of chronic health diseases such as asthma, cardiology, and respiratory diseases in people experiencing homelessness. But there is no literature on the prevalence of obstructive sleep apnea (OSA) in the people experiencing homelessness. OSA is a condition characterized by repeated episodes of breathing cessation during sleep. Patients with OSA can suffer from daytime sleepiness, fatigue, and lack of energy. OSA is also associated with the conditions that account for the leading causes of mortality in adults: hypertension, cardiovascular, and cerebrovascular diseases. Seeing as the people experiencing homelessness already face many societal barriers to healthcare access, it is likely that there may exist a higher prevalence of undiagnosed OSA among the people experiencing homelessness.

Rationale:

From past studies, chronic diseases have been shown to be of higher prevalence in the people experiencing homelessness versus the general population, with an emphasis on a high prevalence of asthma and hypertension in the people experiencing homelessness. There is already a well-established connection between the prevalence of OSA in patients who have asthma and/or hypertension and OSA is already a highly undiagnosed condition in the general population. OSA also contributes to many other chronic health conditions. Given the strong association of hypertension and asthma with OSA, and the above average prevalence of both asthma and hypertension, among other chronic diseases, in this population, it is reasonable to infer that there might also be a high prevalence of undiagnosed OSA among the people experiencing homelessness. The use of technology and telemedicine will decrease the barriers in receiving care for people experiencing homelessness and allow for ease of access to diagnose OSA.

Inclusion/Exclusion Criteria:

研究设计

研究类型
Interventional
分配方式
Non Randomized
干预模型
Single Group
主要目的
Diagnostic
盲法
None

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Residing in a shelter at the time of recruitment
  • Age >18 years old

排除标准

  • Allergies to medical tape [for diagnosis study].
  • Requiring extensive dental treatment or periodontal disease with tooth mobility [for treatment study].

结局指标

主要结局

To assess the prevalence of sleep apnea in shelter residents.

时间窗: up to 4 years.

Understanding the prevalence of sleep apnea in people experiencing homelessness

Changes of FOSQ-10 as an indicator of sleep-related quality of life score over the course of treatment period

时间窗: 3 and 6 month after starting the treatment

Understanding the effect of providing treatment on different aspects of quality of life

The effect of sleep apnea treatment on blood pressure in people experiencing homelessness

时间窗: 3 and 6 month after starting the treatment

Understanding the potential impact of sleep apnea treatment on blood pressure (as an index of cardiorespiratory condition)

Contributing factors to adherence rate (number of nights with treatment usage >4 hours / total number of nights monitored) at months 3 and 6 post-treatment.

时间窗: 3 and 6 month after starting the treatment

To investigate the factors that affect the adherence to preferred sleep apnea treatment in people experiencing homelessness

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Azadeh Yadollahi

Senior Scientist and Associate Professor

University Health Network, Toronto

研究点 (4)

Loading locations...

相似试验

Digital Technology for Sleep and Homelessness | 临床试验