Normal Brain Imaging Database for Brain Disorder Studies
概览
- 阶段
- 不适用
- 干预措施
- 未指定
- 疾病 / 适应症
- Healthy
- 发起方
- University of Manitoba
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- functional connectivity
- 状态
- 进行中(未招募)
- 最后更新
- 去年
概览
简要总结
Healthy volunteers will be recruited. All subjects will be tested a battery of neuropsychological tests, then undergo fluorodeoxyglucose-positron emission tomography (PET) and magnetic resonance imaging (MRI). During the PET and MRI, they will be stimulated with transcranial direct current stimulation (tDCS) for 15 minutes. A third of subjects will receive real tDCS on the left prefrontal cortex, a third on the right prefrontal cortex, and the other third will receive sham tDCS.
研究者
Ji Hyun Ko, PhD
Assistant Professor
University of Manitoba
入排标准
入选标准
- 未提供
排除标准
- •History of any neurological or psychiatric diseases;
- •Abnormal MRI;
- •metal implants or a cardiac pacemaker;
- •Pregnant or breastfeeding women (female subjects of child bearing potential will be screened for pregnancy before MRI imaging).
- •severe hypertension.
- •cardiovascular disease.
- •Family history of epilepsy.
结局指标
主要结局
functional connectivity
时间窗: immediate (less than 30 minutes)
The functional connectivity of the right caudate nucleus will be estimated using graph theory analysis technique of resting-state fMRI.
次要结局
- Stroop task performance(immediate (less than 60 minutes))