EUCTR2008-007336-17-AT进行中（未招募）不适用
Blockade of the greater occipital nerve in frequent migraine and medication-overuse headache - a double-blinded, randomized, controlled trial
Medizinische Universität Wien, Uni. Klinik für Neurologie0 个研究点开始时间: 2009年7月16日最近更新:
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 发起方
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional clinical trial of medicinal product
入排标准
- 性别
- All
入选标准
- •-Men or women, aged between 18 and 65 years
- •-Headache diagnoses
- •a)Study 1: Diagnosis of migraine without or with aura according to the criteria of ICHD-II (Tables 1 and 2) and eight or more days of migraine without aura or probable migraine without aura (Table 3) per month on average during the three months preceding study inclusion.
- •b) Study 2: Diagnosis of MOH according to the revised criteria by Silberstein et al. (ICHD-IIR)
- •-Prophylactic therapy of headache: No prophylactic medication and no non-pharmacological headache prophylaxis in the previous three months OR stable prophylactic therapy for three months continued without change throughout the entire study period.
- •-Written informed consent
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1.2 Adults (18-64 years) yes
- •F.1.2.1 Number of subjects for this age range 158
- •F.1.3 Elderly (>=65 years) no
- •F.1.3.1 Number of subjects for this age range
排除标准
- •-Other headache disorders except tension-type headache
- •-Lifetime history of moderate or severe traumatic brain injury or any other cerebral disorder
- •-Mild traumatic brain injury in the previous year
- •-Substance abuse and medication overuse:
- •Study 1: Lifetime history of substance abuse and medication overuse as defined by Silberstein et al. in the previous year.
- •Study 2: Lifetime history of substance abuse except overuse of acute headache medication. Unsuccessful withdrawal therapy for MOH in the previous year. Current overuse of opioids or benzodiazepines
- •-Diabetes mellitus
- •-Known Glaucoma
- •-Uncontrolled hypertension
- •-Known osteoporosis
- •-Gastral or duodenal ulcer in the previous year
- •-Severe liver disease
- •-Obesity (BMI>30)
- •-Current treatment with corticosteroids
- •-Pregnancy or breastfeeding
- •-Change of prophylactic headache treatment in past 8 weeks
研究者
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