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Clinical Trials/IRCT201107233449N8
IRCT201107233449N8
Completed
未知

Evaluating N-acetylcysteine efficacy in the prevention of amphotericin B-induced nephrotoxicity

Tehran University of Medical Sciences0 sites60 target enrollmentTBD
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ConditionsFungal infections.Certain infectious and parasitic diseasesB37? B38 ?

Overview

Phase
未知
Intervention
Not specified
Conditions
Fungal infections.
Sponsor
Tehran University of Medical Sciences
Enrollment
60
Status
Completed
Last Updated
8 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSimilar Trials

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
TBD
End Date
TBD
Last Updated
8 years ago
Study Type
Interventional
Sex
All

Investigators

Eligibility Criteria

Inclusion Criteria

  • •1\- Age between 18 to 65 years
  • •2\- Hemodynamica stability (Mean arterial pressure \> 70 mmHg and Systolic blood pressure \> 90 mmHg)
  • •3\- Receiving AmB for treatment of fungal infections
  • •Exclusion criteria
  • •1\- Documented history of acute kidney injury or chronic kidney disease
  • •2\- The status of kidney function at baseline is unknown
  • •3\- Receiving N\-acetylcysteine (oral or parenteral) recently (during the last 1 month)
  • •4\- Documented history of hypersensitivity/anaphylactic reactions to N\-acetylcysteine
  • •5\- Co\-administration of antioxidants (e.g. vitamin E, vitamin C)

Exclusion Criteria

  • Not provided

Outcomes

Primary Outcomes

Not specified

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