Evaluation of the efficacy of Hydroxyurea administration on blood oxygen saturation of COVID-19 patients

Not Applicable

Recruiting

• Conditions: COVID-19.; COVID-19, virus identified; U07.1

• Registration Number: IRCT20210901052358N2
• Lead Sponsor: Shahid Beheshti University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 4 April 2022

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 10

Inclusion Criteria

Laboratory confirmation of Coronavirus disease-19 (COVID-19) virus by reverse transcription- polymerase chain reaction (RT-PCR)
Oxygen saturation less than 90%
Respiratory rate more than 24 per minute
More than 50% involvement of the lung parenchyma on CT scan

Exclusion Criteria

White blood cell count less than 2500 million cells per microliter
Absolute neutrophil count less than 1000 million cells per microliter
Platelet count less than 80,000 cells per microliter
More than 50% increase in creatinine compared to the amounts of admission time
Pregnancy
Active hepatitis B or C infections

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Peripheral blood oxygen saturation. Timepoint: Every other day after starting treatment (up to a week). Method of measurement: Pulseoxymeter.;Hemoglobin F levels. Timepoint: Every other day after starting treatment (up to a week). Method of measurement: Hemoglobin electrophoresis.;Blood cell count. Timepoint: Every other day after starting treatment (up to a week). Method of measurement: Laboratory report.