Vitamin D Supplementation for Severe Pneumonia in Under-five Children: A Double Blind, Randomized Placebo Controlled Trial

Indian Council of Medical Research0 个研究点目标入组 324 人开始时间: 待定最近更新: 2022年10月17日

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•Exclusion criteria
•1.Children who have received vitamin D or calcium supplements within last 4 weeks, as ascertained on verbal enquiry (ingestion of oral formulation as sachets/granules or syrups or tablets). Where ever possible the parents will be asked to show the prescription of the physician or empty bottles, sachets or tablets consumed by the child.
•2.Children with clinical features of rickets
•3.Children with severe malnutrition (weight for height less than -3 SD of WHO standards or presence of bipedal edema)
•4.Known asthmatics
•5.Those with complicated pneumonia (lung abscess, pleural effusion, empyema) or illness severe enough to require ventilation.
•6.Those suffering from any chronic respiratory disease including respiratory tract malformations and chest wall deformities, heart disease (congenital/acquired), renal or hepatic insufficiency, neurological illness resulting in abnormalities of muscle tone/power
•7.Those known to have hypercalcemia or allergy to vitamin D
•8.Children immunized with pneumococcal/flu vaccine
•9.Known immunodeficiency

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