Comparison of heart rate and blood pressure changes between propofol and ketofol(ketamine and propofol) as sleep inducing agents in patients undergoing keyhole surgeries under general anaesthesia
Not Applicable
- Conditions
- Health Condition 1: K353- Acute appendicitis with localizedperitonitis
- Registration Number
- CTRI/2022/09/046000
- Lead Sponsor
- S NIJALINGAPPA MEDICAL COLLEGE AND HSK HOSPITA
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1 .ASA 1 and ASA 2 patients
2.Patients aged between 18-60 years
3.Patients undergoing elective laparoscopic surgery.
Exclusion Criteria
1. Patient refusal to give consent
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2. Patients with uncontrolled hypertension
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3. Patients with uncontrolled diabetes mellitus
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4. Patients with history of psychiatric illness
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5. Pregnant patients
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6. Patients with BMI >30kg/m2
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7. Patients with known allergy to study drugs
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What are the molecular mechanisms by which ketofol modulates hemodynamics compared to propofol in laparoscopic surgery patients?
How does the combination of ketamine and propofol in ketofol affect cardiovascular stability versus propofol alone during general anesthesia induction?
Are there specific biomarkers that predict differential hemodynamic responses to propofol or ketofol in patients with acute appendicitis undergoing laparoscopic procedures?
What adverse events are associated with ketofol use in laparoscopic surgery and how do they compare to propofol-induced hypotension management strategies?
How does ketofol's opioid-sparing effect during anesthesia induction compare to other propofol-based combination agents in abdominal surgical settings?