NCT02982356Unknown不适用
Prenatal Screening, Diagnosis and Intrauterine Intervention of Fetal Abnormal Chromosome and Structure in Twins Pregnancy
适应症
干预措施
相关药物
试验速览
- 阶段
- 不适用
- 入组人数
- 1,300
- 主要终点
- Success rate for the operation
研究概览
简要总结
The risk of abnormal chromosome and structure is much higher in twins than in singletons, and traditional early pregnancy screening strategy for single pregnancy is not suitable for twins. Based on our management experience of fetal medicine at twin pregnancy, and multi-center cooperation, the study will carry out the following clinical studies:
- to explore a suitable, early, noninvasive and accurate prenatal screening strategy for twin pregnancy.
- fetal chromosomal abnormalities
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 45 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •ultrasound diagnosis as twin pregnancy
- •at 11-14 gestational weeks
排除标准
- •Multiple pregnancies (three or more)
- •Maternal history of chromosome aneuploidy abnormality or tumor
研究组 & 干预措施
Fetal Selective Reduction Technology
Other
Potassium chloride fetal heart injection in the dichorial twins with abnormal chromosome and structure
干预措施: Fetal Selective Reduction Technology (Procedure)
Fetal Selective Reduction Technology
Other
Potassium chloride fetal heart injection in the dichorial twins with abnormal chromosome and structure
干预措施: Potassium Chloride (Drug)
结局指标
主要结局
Success rate for the operation
时间窗: 1 week
次要结局
- long-term complications after surgery(1 year)
研究者
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