Cross-sectional study on bile acid reflux and Barrett's esophagus, Gastro Esophageal Reflux Disease
- Conditions
- Barrett's esophagus, Gastro Esophageal Reflux Disease
- Registration Number
- JPRN-UMIN000044301
- Lead Sponsor
- Yokohama City University Hospital
- Brief Summary
Patients with Barrett's esophagus have higher total bile acid concentration (total BA) and certain bile acid fraction concentrations (e.g. Conj CDCA). The Spearman rank correlation coefficient between total BA and Conj CDCA is strongly correlated at 0.95. Total BA, Conj CA, and Conj CDCA are strongly correlated with the color of gastric juice. The color of the intragastric liquid was quantified to obtain a cutoff value (Youden Index) for the presence of Barrett's esophagus (YI 11.3).
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 436
Not provided
Patients who require emergency treatment and are difficult to observe normally
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Relationship between intragastric bile acid concentration and Barrett's esophagus and Gastro Esophageal Reflux Disease
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.