Cerebral and Cognitive Markers of Treatment Resistance in Obsessive Compulsive Disorder

Recruiting

• Conditions: OCD

• Registration Number: NCT05843604
• Lead Sponsor: Centre Hospitalier Henri Laborit

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2023-4-25
• Last Update Posted: 2 September 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

Inclusion Criteria:<br><br> - Obsessive compulsive disorder diagnosed according to Diagnostic and Statistical<br> Manual 5 criteria (patients will be included regardless of the severity and<br> resistance of their pathology and their levels of executive functions)<br><br> - Understand and accept the constraints of the study<br><br> - Be a beneficiary or affiliated to a Health Insurance scheme<br><br>Exclusion Criteria:<br><br> - Present one of the diagnoses according to the criteria of the DSM 5: schizophrenic<br> disorders, substance abuse or dependence to a substance according to the criteria of<br> the M.I.N.I. version 5.0 (Sheehan et al., 1998)<br><br> - Generalized anxiety disorder, social anxiety, nicotine dependence and history of a<br> major depressive episode are not exclusion criteria according to the M.I.N.I.<br> version 5.0 (Sheehan et al., 1998)<br><br> - Have a serious intercurrent pathology<br><br> - Being a pregnant woman<br><br> - Being a woman of childbearing age without effective contraception.<br><br> - Being hospitalized under duress or on an outpatient basis in a care program<br><br> - Being under judicial protection (reinforced curatorship, guardianship)

Exclusion Criteria

Not provided

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Cerebral activity modification during N-back task;Cerebral activity modification during Stroop task;Cerebral activity modification during switching task (Monsell et Mizon task )