Effect of tDCS (A brain stimulation treatment) on the symptom of hearing voices experienced in schizophrenia (a mental disorder)

Not Applicable

Completed

• Registration Number: CTRI/2014/12/005307
• Lead Sponsor: ational Institute of Mental Health and Neurosciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2016-05-31
• Last Update Posted: 22 January 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 25

Inclusion Criteria

1) Diagnosis of schizophrenia / schizophreniform disorder as per DSM-V criteria (Diagnostic and Statistical Manual for Mental Disorders, American Psychiatric Association, 2013);

2) Clinically Significant Auditory Verbal Hallucinations as defined by the Auditory Hallucination Rating Scale (Haddock et al., 1999) items on frequency, duration and disruption each having a score = 2;

3) Persistence of Auditory Verbal Hallucinations as denoted by daily hallucinations without remission despite adequate treatment with antipsychotic medication at an adequate dosage for at least 3 months (Brunelin et al., 2012a)

4) Age range: 18 – 45 years;

5) Both sexes;

6) Right Handedness and

7) Written informed consent.

Exclusion Criteria

1. Features suggestive of psychiatric emergency (for example: suicidal risk, aggression, excitement, catatonia, prolonged nutritional deprivation or any other status requiring intensive clinical care)

2. Pregnancy or post-partum status

3. Any contraindication to tDCS procedure (metal in the head, implanted brain medical devices, local lesion or injury in the scalp / head)

4. Any contraindication for MRI

5. Any co-morbid psychiatric or neurological diagnosis

6. Left/Mixed Handedness

Study & Design

• Study Type: Interventional
• Study Design: Not specified