Cardiovascular evaluation Exercise in patients with Sjogren's Syndrome

Not Applicable

• Conditions: Sjogren's syndrome; M35.0

• Registration Number: RBR-3v3zmd
• Lead Sponsor: niversidade Federal de São Paulo

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2017-06-20
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Recruitment completed
• Sex: Female
• Target Recruitment: Not specified

Inclusion Criteria

Women with diagnosis of primary Sjogren's syndrome confirmed by the revised Classification Criteria of 2002; age between 18 and 90 years; understanding and signing of the free and informed consent term.

Exclusion Criteria

Diagnosis of heart, lung, endocrine, or any other disease that impedes the practice of exercise;
Inflammatory joint activity that impedes the practice of exercise; Regular exercise for more than 4 weeks in the last 6 months.

Study & Design

• Study Type: Intervention
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
15% improvement in maximum oxygen consumption (VO2max) measured by ergospirometry in relation to baseline, performed at the beginning of the study and up to 72 hours after the last training.

Secondary Outcome Measures

Name	Time	Method
Improvement of respiratory threshold and maximal heart rate as measured by ergospirometry; improvement of ejection fraction and left ventricular systolic and diastolic functions, measured by echocardiography; improvement of glycemic and lipemic profiles; improvement in the quality of life measured by the SF 36 questionnaire; maintenance of the disease activity index measured by the ESSDAI questionnaire. All measurements were taken up to 72 hours after the last training.