Skip to main content
Clinical Trials/NCT05552365
NCT05552365
Completed
N/A

Randomised Pilot Control Trial for Reducing Anxiety Problems Among Children Indicated to Have Developmental Language Disorder

Nanyang Technological University1 site in 1 country9 target enrollmentDecember 16, 2022

Overview

Phase
N/A
Intervention
Not specified
Conditions
Developmental Language Disorder and Language Impairment
Sponsor
Nanyang Technological University
Enrollment
9
Locations
1
Primary Endpoint
Anxiety Disorders Interview Schedule (ADIS-IV; Brown et al., 2004)
Status
Completed
Last Updated
last year

Overview

Brief Summary

This study aims to pilot a world-first intervention, a mental health intervention augmented for children indicated with developmental language disorder (DLD). It serves as a proof-of-concept of how existing observational studies on these topics at the Centre for Research in Child Development (c.f. Tran-Sen; Gibber) can be translated into interventions. Mental health problems here are defined as anxiety type problems of social anxiety, specific phobia, separation anxiety and generalised anxiety. DLD is defined as a marked difficulty in oral language in the absence of biomedical causes (Bishop et al., 2017). This randomised pilot answers three uncertainties in preparation for a future definitive randomised control trial (RCT).

Detailed Description

This pilot aims to answer three uncertainties for a future randomised control trial (RCT), namely (1) Is the proposed intervention's efficacy sufficient (2) Are the proposed methods of recruitment sufficient (3) Are the proposed measures of evaluation sufficient Hypotheses: (1) Piloted intervention is sufficient for definitive RCT as 90% confidence intervals contain expected improvement versus treatment-as-usual (2) Piloted recruitment methods are sufficient for definitive RCT as recruitment rate is \>4/month, dropout rate\<25%. (3) Piloted measures are sufficient for definitive RCT as rates of unusable data are \<20% and reliability alpha \>.70.

Registry
clinicaltrials.gov
Start Date
December 16, 2022
End Date
October 31, 2024
Last Updated
last year
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Shaun Goh Kok Yew

Lecturer

Nanyang Technological University

Eligibility Criteria

Inclusion Criteria

  • Shows signs of elevated anxiety, fear or stress, as rated on anxiety measures conducted by this study
  • Enrolled in Primary 1 to 6 in a Ministry of Education Primary School
  • Signs of a language difficulty \[Either one of the following\]
  • Existing clinical opinion/report of this when child \>5 years old
  • Score \<10th percentile on language measures conducted by this study

Exclusion Criteria

  • Conditions which exclude Developmental Language Disorder (e.g. Autism, Intellectual Disability, Hearing Impairment, other biomedical conditions).
  • Non-anxiety disorder as primary mental health disorder
  • Currently receiving treatment for anxiety disorder (e.g. pharmacotherapy or psychotherapy).

Outcomes

Primary Outcomes

Anxiety Disorders Interview Schedule (ADIS-IV; Brown et al., 2004)

Time Frame: Administered at post treatment which is a maximum of 4 weeks from final session

The ADIS-IV is a semi-structured interview organised diagnostically to permit differential diagnoses of anxiety disorders. Its yields a severity rating (0 to 8) which is utilised here as the primary outcome

Secondary Outcomes

  • Screen for child anxiety related emotional disorders (SCARED; Birmaher et al., 1999)(Administered at post treatment which is a maximum of 4 weeks from final session)
  • Child Anxiety Life Interference Scale (CALIS; Lyneham, et. al., 2013)(Administered at post treatment which is a maximum of 4 weeks from final session)

Study Sites (1)

Loading locations...

Similar Trials