Comparison of Two Airway Clearance Techniques by Electrical Impedance Tomography- a Parallel Study
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 30
- 试验地点
- 4
- 主要终点
- end-expiratory lung impedance
研究概览
简要总结
The goal of this clinical trial is to compare the effectiveness of two airway clearance techniques for patients with ventilator associated pneumonia. The main questions it aim to answer are:
- effect of the therapies on volume changes
- outcome on sputum clearance Participants will receive airway clearance techniques of
- chest physiotherapy
- high frequency chest wall oscillation.
详细描述
Sputum can be accumulated in the airways of intubated patients, resulting in recurrent pneumonia. The airway clearance therapy is often utilized with chest physiotherapy or high frequency chest wall oscillation which has become popular for its easy of use and less time consuming to the healthcare workers. The main questions it aim to answer are on effectiveness of the therapies on lung volume changes and sputum clearance by two airway clearance techniques. With the oscillation of entire chest wall, the investigators hypothesize that the high frequency chest wall oscillation is more effectively clear sputum in the distal airways.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
盲法说明
The group will be coded and mask to the investigator and the outcome accessor.
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Diagnosed with chronic pulmonary disease
- •Diagnosed with ventilator associated pneumonia
- •Receive airway clearance therapy
排除标准
- •Head injury, spinal injury
- •Instable hemodynamics
- •Intercranial pressure > 20 cmH2O
- •Active hemoptysis
- •Eye surgery
- •Abdominal distension
- •Chest tube insertion
- •Active tuberculosis
结局指标
主要结局
end-expiratory lung impedance
时间窗: Measurement before intervention, 30 after, 1 hour and 2 hours after intervention
Changes of global of impedance of lungs measure by the electrical impedance tomography
次要结局
- Weight of secretions(Sputum is collected before intervention, 30 after, 1 hour and 2 hours after intervention)
研究者
Hui-Ling Lin
Professor
Chang Gung University