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Clinical Trials/NCT06032871
NCT06032871
Recruiting
Not Applicable

Comparison of Two Airway Clearance Techniques by Electrical Impedance Tomography- a Parallel Study

Hui-Ling Lin2 sites in 1 country30 target enrollmentMarch 16, 2023

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Airway Clearance Impairment
Sponsor
Hui-Ling Lin
Enrollment
30
Locations
2
Primary Endpoint
end-expiratory lung impedance
Status
Recruiting
Last Updated
2 years ago

Overview

Brief Summary

The goal of this clinical trial is to compare the effectiveness of two airway clearance techniques for patients with ventilator associated pneumonia. The main questions it aim to answer are:

  • effect of the therapies on volume changes
  • outcome on sputum clearance Participants will receive airway clearance techniques of
  • chest physiotherapy
  • high frequency chest wall oscillation.

Detailed Description

Sputum can be accumulated in the airways of intubated patients, resulting in recurrent pneumonia. The airway clearance therapy is often utilized with chest physiotherapy or high frequency chest wall oscillation which has become popular for its easy of use and less time consuming to the healthcare workers. The main questions it aim to answer are on effectiveness of the therapies on lung volume changes and sputum clearance by two airway clearance techniques. With the oscillation of entire chest wall, the investigators hypothesize that the high frequency chest wall oscillation is more effectively clear sputum in the distal airways.

Registry
clinicaltrials.gov
Start Date
March 16, 2023
End Date
June 30, 2024
Last Updated
2 years ago
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Sponsor
Hui-Ling Lin
Responsible Party
Sponsor Investigator
Principal Investigator

Hui-Ling Lin

Professor

Chang Gung University

Eligibility Criteria

Inclusion Criteria

  • Diagnosed with chronic pulmonary disease
  • Diagnosed with ventilator associated pneumonia
  • Receive airway clearance therapy

Exclusion Criteria

  • Head injury, spinal injury
  • Instable hemodynamics
  • Intercranial pressure \> 20 cmH2O
  • Active hemoptysis
  • Eye surgery
  • Abdominal distension
  • Chest tube insertion
  • Active tuberculosis

Outcomes

Primary Outcomes

end-expiratory lung impedance

Time Frame: Measurement before intervention, 30 after, 1 hour and 2 hours after intervention

Changes of global of impedance of lungs measure by the electrical impedance tomography

Secondary Outcomes

  • Weight of secretions(Sputum is collected before intervention, 30 after, 1 hour and 2 hours after intervention)

Study Sites (2)

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