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Clinical Trials/NCT03031002
NCT03031002
Completed
Not Applicable

Extinction Generalization in Exposure Therapy for Spider Phobia

Ruhr University of Bochum0 sites77 target enrollmentFebruary 2015
ConditionsSpecific Phobia

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Specific Phobia
Sponsor
Ruhr University of Bochum
Enrollment
77
Primary Endpoint
Change in the Behavioral Approach Test (BAT) from pre- to posttreatment
Status
Completed
Last Updated
9 years ago

Overview

Brief Summary

Patients with anxiety disorders oftentimes express fear responses to more than only one fear-inducing object. The principal aim of this study is to examine whether the beneficial effects of exposure on fear reduction in spider phobia can extend to stimuli which are conceptually similar to spiders (i.e. cockroaches), but have never been presented during the respective treatment.

Detailed Description

Fear extinction has evolved as the central mechanism underlying exposure-based treatments. Findings from conditioning studies indicate that fear reduction following a fear extinction procedure can generalize from the extinction stimulus to other conceptually and perceptually related stimuli. This study is aimed at translating these findings to a clinical application and will hence examine whether the basic principles of extinction generalization are applicable to exposure. Patients with spider phobia will either receive two sessions of in-vivo exposure with spiders or no treatment. Prior to as well as after treatment, patient's fear of spiders will be assessed using the Behavioral Approach Test (BATs) and self-report questionnaires. In addition, BATs with cockroaches will be conducted to examine the effects of exposure therapy on extinction generalization.

Registry
clinicaltrials.gov
Start Date
February 2015
End Date
July 2016
Last Updated
9 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Ruhr University of Bochum
Responsible Party
Principal Investigator
Principal Investigator

Armin Zlomuzica

Dr.

Ruhr University of Bochum

Eligibility Criteria

Inclusion Criteria

  • spider phobia according to Diagnostic and Statistical Manual of Mental Disorders (DSM) -IV criteria

Exclusion Criteria

  • any neurological or neuropsychiatric condition
  • current behavioral or pharmacological treatment
  • any mental disorder that is considered more severe than specific phobia

Outcomes

Primary Outcomes

Change in the Behavioral Approach Test (BAT) from pre- to posttreatment

Time Frame: Pre- and Posttreatment (with approximately 4 days between pre- and posttreatment)

Behavioral Approach Tests with Spiders and Cockroaches will be conducted at pre- and posttreatment. Here, the closest proximity a participant is able to attain to the spider/cockroach will be measured.

Secondary Outcomes

  • Change in Heart Rate during the Behavioral Approach Tests (BATs) from pre- to posttreatment(Pre- and Posttreatment (with approximately 4 days between pre- and posttreatment))
  • Change in the Spider Phobia Questionnaire (SPQ)(Pre- and Posttreatment (with approximately 4 days between pre- and posttreatment))
  • Change in the Spider Beliefs Questionnaire (SBQ)(Pre- and Posttreatment (with approximately 4 days between pre- and posttreatment))
  • Change in the Fear of Spiders Questionnaire (FSQ)(Pre- and Posttreatment (with approximately 4 days between pre- and posttreatment))
  • Change in Subjective Fear / Disgust during the Behavioral Approach Tests (BATs) using the Subjective Units of Distress Scale (SUDS)(Pre-and Posttreatment (with approximately 4 days between pre- and posttreatment))

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