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Financial Incentives to Translate ALLHAT Into Practice: A Randomized Trial

Not Applicable
Completed
Conditions
Hypertension
Interventions
Behavioral: Physician- and practice-level financial incentives
Behavioral: Physician-level financial incentives
Behavioral: Practice-level financial incentives
Registration Number
NCT00302718
Lead Sponsor
VA Office of Research and Development
Brief Summary

The purpose of this study was to determine whether financial incentives for guideline-recommended treatment of hypertension are effective. We hypothesized that patients with hypertension cared for by physicians or practice groups receiving financial incentives were more likely to be prescribed guideline-recommended anti-hypertensive medications and achieve Joint National Commission (JNC) 7 guideline-recommended blood pressure goals compared to patients who were treated by providers that did not receive financial incentives.

Detailed Description

Background:

Despite compelling evidence of the benefits of treatment, hypertension is controlled in less than one-quarter of US citizens. Using a cluster randomized controlled trial, we tested the effect of explicit physician-level and practice-level financial incentives to promote the provision of guideline-recommended anti-hypertensive medications and improved control of hypertension in the VA primary care setting.

Objectives:

The goals were to: (1) determine the effect of physician-level financial incentives on processes and outcomes of care for outpatients with hypertension; (2) assess the impact of practice-level incentives; (3) ascertain whether there were additive or synergistic effects of physician- and practice-level incentives; (4) evaluate the persistence of the effect of incentives after the intervention ceases; and (5) identify any negative impacts of incentives on patients, providers, or health care organizations.

Methods:

We randomized 12 VA hospital-based outpatient clinics to the following arms: (1) physician-level incentives; (2) practice-level incentives; (3) physician- and practice-level incentives; and (4) no incentives. We enrolled 83 primary care physicians and 42 practice group members (e.g., nurses). All participants received audit and feedback performance reports. Study measures included the use of guideline-recommended anti-hypertensive medications and the proportion of patients who achieved national (JNC 7) guideline-recommended blood pressure goals or received an appropriate response to uncontrolled blood pressure. The intervention period consisted of five four-month performance periods. For each period, trained reviewers collected medications, blood pressure readings, comorbid conditions, medication allergies, and lifestyle recommendations from the VA electronic health record system for a sample of eligible patients from the physicians' panels. After the final performance report, we implemented a 12-month washout period. To determine the impact of incentives for the intervention period, we performed a repeated-measures longitudinal analysis using the hospital as a random effect. We evaluated the rate of change in the proportion of patients who met the study measures over time for the intervention group physicians. We assessed post-washout performance using a linear analysis with clustering by hospital. To evaluate unintended consequences of the incentives, we examined the incidence of hypotension in the physicians' panels.

Status:

The study is completed. The primary findings were published in September 2013 in the Journal of the American Medical Association (JAMA). We are currently preparing manuscripts describing findings from the study's secondary aims.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
83
Inclusion Criteria

Study participants had to be full-time primary care physicians employed by the Veterans Health Administration (VA) at one of the 12 VA hospitals that participated in the study.

We defined a full-time primary care physician as spending at least 0.60 full-time equivalent (FTE) delivering patient care services in the primary care setting or having a panel size of at least 500 patients at the time of study arm randomization. The primary care settings included internal medicine, primary care medical clinics, and women's health care clinics. The trial did not actively recruit patients into the study. This study retrospectively reviewed a random sample of health records of eligible patients that had clinical encounters with the physician participants.

Exclusion Criteria

The study did not include VA physicians that were trainees.

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Physician- and practice-level incentivesPhysician- and practice-level financial incentivesExamines the effect of physician- and practice-level financial incentives on hypertension quality of care
Physician-level incentivesPhysician-level financial incentivesExamines the effect of physician-level financial incentives on hypertension quality of care
Practice-level incentivesPractice-level financial incentivesExamines the effect of practice-level financial incentives on hypertension quality of care
Primary Outcome Measures
NameTimeMethod
Proportion of the Physicians' Patients With Blood Pressure Control or Appropriate Response to Uncontrolled Blood PressureBaseline period (August-November 2007)

This measure reports the unadjusted proportion of physicians' patients meeting the study outcome for the first performance period (baseline). Data are based on review of the electronic health records for 40 patients with hypertension randomly selected from each physician's panel. We used the guidelines from the "Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure (JNC 7)" to determine if the physicians' patients achieved the recommended blood pressures thresholds and if providers appropriately responded to uncontrolled blood pressure. Appropriate responses included increasing the dosage of a guideline-recommended antihypertensive medication or recommending a lifestyle modification to patient with Stage 1 hypertension.

Proportion of Physicians' Patients With Blood Pressure Control or Appropriate Response to Uncontrolled Blood PressureAfter the washout period (May-August 2011)

This measure reports the unadjusted proportion of physicians' patients meeting the study outcome for the post-washout performance period. Data are based on review of the electronic health records for 40 patients with hypertension randomly selected from each physician's panel. We used the guidelines from the "Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure (JNC 7)" to determine if the physicians' patients achieved the recommended blood pressures thresholds and if providers appropriately responded to uncontrolled blood pressure. Appropriate responses included increasing the dosage of a guideline-recommended antihypertensive medication or recommending a lifestyle modification to patient with Stage 1 hypertension.

Proportion of Physicians' Patients Prescribed Guideline-recommended Antihypertensive MedicationsAfter the washout period (May-August 2011)

This measure reports the unadjusted proportion of physicians' patients meeting the study outcome for the post-washout performance period. Data are based on review of the electronic health records for 40 patients with hypertension randomly selected from each physician's panel. We used the "Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure (JNC 7)" to evaluate use of guideline-recommended antihypertensive medications. Assessing use of guideline-recommended medications included collecting information about the patient's compelling conditions (e.g., diabetes mellitus) as well as allergies and refusals to antihypertensive medications.

Secondary Outcome Measures
NameTimeMethod
Hemoglobin (Hb) A1c LevelsFinal intervention period (April-July 2009)

This measure reports the proportion of patients with (Hb)A1c control ((Hb)A1c ≤ 9%) for the fifth and final intervention performance period. We did not measure the pre-specified post washout period results for this secondary outcome. The pre-specified post washout period results were not to be measured if the final intervention period results were not significant.

Low-density Lipoprotein (LDL) Cholesterol LevelsFinal intervention period (April-July 2009)

This measure reports the proportion of patients who had LDL control (LDL cholesterol \< 100) for the fifth and final intervention performance period. We did not measure the pre-specified post washout period results for this secondary outcome. The pre-specified post washout period results were not to be measured if the final intervention period results were not significant.

Colorectal Cancer (CRC) ScreeningFinal intervention period (April-July 2009)

This measure reports the proportion of patients who had at least one of four CRC screens in the appropriate timeframe for the fifth and final intervention performance period. Appropriate CRC screens consisted of at least one of the following: 1) fecal occult blood test every year; 2) barium enema every five years; 3) flexible sigmoidoscopy every five years; 4) colonoscopy every ten years. We did not measure the pre-specified post washout period results for this secondary outcome. The pre-specified post washout period results were not to be measured if the final intervention period results were not significant.

Beta Blocker UseFinal intervention period (April-July 2009)

This measure reports the proportion of patients with beta blocker use at the time of the index visit for the fifth and final intervention performance period. We did not measure the pre-specified post washout period results for this secondary outcome. The pre-specified post washout period results were not to be measured if the final intervention period results were not significant

Trial Locations

Locations (12)

VA Medical Center, Augusta

🇺🇸

Augusta, Georgia, United States

G.V. (Sonny) Montgomery VA Medical Center, Jackson

🇺🇸

Jackson, Mississippi, United States

Aleda E. Lutz VA Medical Center

🇺🇸

Saginaw, Michigan, United States

VA Connecticut Health Care System (Newington)

🇺🇸

Newington, Connecticut, United States

VA Medical Center, Jamaica Plain Campus

🇺🇸

Boston, Massachusetts, United States

VA Medical Center, Providence

🇺🇸

Providence, Rhode Island, United States

VA Medical Center, Oklahoma City

🇺🇸

Oklahoma City, Oklahoma, United States

John D. Dingell VA Medical Center, Detroit

🇺🇸

Detroit, Michigan, United States

VA Medical Center, Birmingham

🇺🇸

Birmingham, Alabama, United States

VA Medical Center, Minneapolis

🇺🇸

Minneapolis, Minnesota, United States

Michael E. DeBakey VA Medical Center, Houston, TX

🇺🇸

Houston, Texas, United States

Ralph H Johnson VA Medical Center, Charleston

🇺🇸

Charleston, South Carolina, United States

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