platelet activation in lung transplantatio

Completed

• Conditions: emphysema; lung failure; 10038716; 10038737

• Registration Number: NL-OMON31994
• Lead Sponsor: niversitair Medisch Centrum Groningen

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 13 May 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 20

Inclusion Criteria

Age >= 18 years
First bilateral lungtransplantation (study population), planned off-pump.
Off-pump coronary artery bypass grafting (control group)
Non-inflammatory disease
Informed consent

Exclusion Criteria

Combined organ transplantations
Use of pre-operative antiplatelet medication
Peroperative use of CPB
Peroperative transfusion of platelet concentrates
Inflammatory diseases (e.g. cystic fibrosis)

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The development of functional properties of primary hemostasis (especially of<br /><br>platelets and vWF) during lung transplantation. The appearance of (partly)<br /><br>activated circulating platelets during lung transplantation, especially after<br /><br>reperfusion of the graft. </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>none</p><br>