Observational Study on the Course of Plasma Glutamine Levels During Critical Illness
- Conditions
- Glutamine Levels
- Registration Number
- NCT02310035
- Lead Sponsor
- Medical Centre Leeuwarden
- Brief Summary
Blood sampled for standard evaluation will be used for determination of plasma glutamine by Bioprofile Flex Glutamine Sensor at ICU admission
- Detailed Description
All patients who are admitted to the ICU after elective surgery and non-elective admissions. In both groups a total of 80 patients will be included.
(In the trials we mentioned in the introduction 80, 174 and 66 patients were included. In the study performed by Oudemans-van Straaten a decent distribution between lower and higher levels of glutamine was achieved in 80 non-elective patients.) Exclusion criteria are patients younger then 18 years and patients who need total parenteral nutrition (TPN).
The patients will receive standard care during their treatment on the ICU. Blood sampled for standard evaluation will be used for determination of plasma glutamine by Bioprofile Flex Glutamine Sensor at ICU admission. Hereafter plasma glutamine will be measured daily, a plasma sample will be taken from a standard evaluation blood sample at 6.00 am during admission on the ICU.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 178
- all patients admitted to the ICU
- younger then 18 years and patients who need total parenteral nutrition
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method glutamine in serum from admission up to 8 days glutamine level at admission and during ICU stay daily
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Medical Centre Leeuwarden
🇳🇱Leeuwarden, Netherlands