the influence of traditional Chinese medicine on the frequency and median recurrence time of dupilumab for patients with moderate and severe atopic dermatitis
- Conditions
- atopic dermatitis
- Registration Number
- ITMCTR2024000055
- Lead Sponsor
- The Second Affiliated Hospital of Guangzhou University of Chinese Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- Not specified
(1) meet the diagnostic criteria of Hanifin and Rajka.
(2) No sex limit, age 6-65 years old
(3) patients with moderate and severe atopic dermatitis, eczema area and severity index (EASI) = 7 or IGA score = 3
(4) the patient himself or his agent agrees to be treated with dupilumab.
(5) patients whose blood system, liver, kidney, heart and other systems are basically normal.
(6) patients with good compliance, who can be injected with dupilumab at a specified time and fill in the data such as the scale regularly.
(1) patients with other skin diseases such as scabies, psoriasis, seborrheic dermatitis that affect the judgment of skin lesions.
(2) patients suffering from mental diseases, malignant tumors, diabetes and heart disease, pregnant and lactating women.
Study & Design
- Study Type
- Observational study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method median recurrence time;relapse rate;
- Secondary Outcome Measures
Name Time Method i-VAS(insomnia visual analog scale);IGA(inventor global assessment);p-VAS(pruritus visual analog scale);DLQI(dermatology life quality index);EASI(eczema area and severity index);POEM(patient oriented eczema measure);SCORAD(scoring for Atopic Dermatitis );