EFFECT OF PAROXETINE AND FLUOXETINE ON GUM HEALTH IN PATIENTS OF DEPRESSION AND PYORRHEA.

Not Applicable

• Conditions: Health Condition 1: F320- Major depressive disorder, singleepisode, mild

• Registration Number: CTRI/2021/11/037995
• Lead Sponsor: DR SINAM SUBHASCHANDRA SINGH

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 21 February 2022

Recruitment & Eligibility

• Status: ot Yet Recruiting
• Sex: Not specified
• Target Recruitment: 0

Inclusion Criteria

1.Patients with depression and periodontitis.

2.Patient should have minimum 20 teeth other than third molars.

Periodontitis criteria

Stage 1 and 2 generalized Periodontitis patients as per the 2017 periodontitis classification

Depression criteria

Diagnosis of depression will be made using ICD-10 criteria,

In typical depressive episodes of all three varieties

a.(mild (F32.0),

b.moderate (F32.1), and

c.severe (F32.2 and F32.3)

Exclusion Criteria

1.History of systemic disease or condition that is reported to be associated with periodontal disease, including diabetes mellitus, osteoporosis, rheumatoid arthritis, chronic renal failure, cardiovascular disease, and pregnancy.

2.Treatment with the following drugs in the previous 3 months: antibiotics, anti-inflammatories, steroids, immunosuppressants, lipid-lowering drugs, anticoagulants, bisphosphonates, and host modulatory drugs.

3.Patients on anyantidepressant medication besides Paroxetine andFluoxetine.

4.Patients who have undergone periodontal treatment (non-surgical or surgical) 6 months prior to the study

Study & Design

• Study Type: Observational
• Study Design: Not specified