Exploratory Research of the Use and Its Timing of Steroid Eye Drops in Bacterial Keratitis

Not Applicable

• Conditions: Bacterial keratitis

• Registration Number: JPRN-UMIN000028535
• Lead Sponsor: Tottori University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2017-09-01
• Study Completion: 2022-03-31
• Last Update Posted: 17 October 2023

Recruitment & Eligibility

• Status: Complete: follow-up complete
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

Not provided

Exclusion Criteria

1)Patients difficult to be obtained the agreement of participation of this study 2)Patients with high possibility of other causative agents than bacteria 3)Patients with perforated cornea or extremely thin cornea 1), 2), or 3)

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To quantify various cytokines by ELISA in tear taken at the first visit and 1, 2, 3, and 4 weeks later in definite and presumed cases of bacterial keratitis.

Secondary Outcome Measures

Name	Time	Method
To analyze various RNA comprehensively and quantify bacterial 16s ribosomal-DNA in corneal scrapings taken at the first visit and 2 weeks later or before the start of steroid eye drops in definite and presumed cases of bacterial keratitis.