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Clinical Trials/NCT02521428
NCT02521428
Completed
Not Applicable

End-of-Life Decisions in Surgical Intensive Care Medicine - The Relevance of Treatment Withholding

Charite University, Berlin, Germany0 sites226 target enrollmentAugust 2008
ConditionsQuality of Life

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Quality of Life
Sponsor
Charite University, Berlin, Germany
Enrollment
226
Primary Endpoint
sequence of withdrawing life-sustaining treatment
Status
Completed
Last Updated
10 years ago

Overview

Brief Summary

The purpose of this retrospective observational study is to describe the sequence of ICU-therapies that are limited and to compare characteristics and the decision making process in surgical ICU-patients.

Detailed Description

Decisions to limit life-support therapy are common on the intensive care unit (ICU). End-of-life decisions (EOLD) underlie a dynamic process and limitation of ICU-therapies is done sequentially. Questionnaire-based and observational studies on medical ICUs and in palliative care reveal blood transfusions as the first therapy physicians withhold in EOLDs. Whether this practice also applies to surgical ICU-patients is unknown. The purpose of this retrospective observational study is to describe the sequence of ICU-therapies that are limited and to compare characteristics and the decision making process in surgical ICU-patients.

Registry
clinicaltrials.gov
Start Date
August 2008
End Date
August 2015
Last Updated
10 years ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Jan Adriaan Graw

Dr. med.

Charite University, Berlin, Germany

Eligibility Criteria

Inclusion Criteria

  • All surgical patients admitted to the ICU All surgical patients discharged death from the ICU

Exclusion Criteria

  • All patients discharged alive from the ICU

Outcomes

Primary Outcomes

sequence of withdrawing life-sustaining treatment

Time Frame: 3 years

The primary objective of this study performed according to an observational post-ad-hoc design is to identify the sequence of withdrawing life-sustaining treatment in surgical ICU-patients with an end-of-life decision on an intensive care unit of a German academic medical center. Approximately 200 patients will be enrolled in the study. They are followed up until their death on the ICU. In clinical routine end-of-life decisions are documented for decision-makers and procedures in the patients´ records. Patients´ characteristics and therapeutic approaches are documented in the electronic patient data management system.

Secondary Outcomes

  • factors associated with the withholding of specific ICU-therapies(3 years)

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