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Clinical Trials/NCT06414109
NCT06414109
Completed
N/A

Mindfulness-Based Intervention for Adolescents With Chronic Migraine

University of Colorado, Denver1 site in 1 country17 target enrollmentJune 4, 2024

Overview

Phase
N/A
Intervention
Not specified
Conditions
Migraine
Sponsor
University of Colorado, Denver
Enrollment
17
Locations
1
Primary Endpoint
Intervention feasibility
Status
Completed
Last Updated
10 months ago

Overview

Brief Summary

The goal of this study is to assess feasibility and acceptability of a mindfulness-based intervention adapted for adolescents with migraine to inform a future randomized trial assessing effects of the intervention on headache-related outcomes.

Detailed Description

Mindfulness-based intervention (MBI) shows promise in adults with migraine, but research is limited in adolescents. The current study aims to advance behavioral treatments for adolescents with frequent migraine by adapting an existing empirically-supported MBI for adolescents (Learning to BREATHE) to meet the unique needs of adolescents with chronic migraine. In Phase I of the study, we will use feedback solicited from interviews with teens with chronic migraine, their parents, and healthcare providers documenting the experience of living with chronic migraine and on the content and delivery of the MBI to create an adapted telehealth group intervention specifically tailored for adolescents with frequent migraine. In Phase II of the study, the adapted MBI will be piloted in a single-arm trial with adolescents with frequent migraine to assess feasibility, acceptability, and preliminary clinical signals.

Registry
clinicaltrials.gov
Start Date
June 4, 2024
End Date
May 23, 2025
Last Updated
10 months ago
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Age 13 to 18 years
  • Diagnosed with migraine by medical provider using criteria from the International Classification of Headache Disorders, Third Edition
  • Patient report of \>= 8 headache days per month
  • PedMIDAS Score of \> 10 (at least mild headache-related disability)

Exclusion Criteria

  • Major comorbid medical condition (e.g., cancer, epilepsy)
  • Active psychosis or suicidal ideation
  • Inability to provide consent/assent

Outcomes

Primary Outcomes

Intervention feasibility

Time Frame: Up to 6 weeks

Percent of sessions attended; Qualitative data generated via focus group interviews (questions will include barriers and facilitators to completing the intervention)

Intervention acceptability

Time Frame: 7 weeks

Ratings on program acceptability questionnaire (higher scores indicate higher acceptability); Qualitative data generated via focus group interviews (questions will include positive and negative perceptions of the intervention)

Secondary Outcomes

  • Change in headache-related disability(Baseline, 6 weeks)
  • Change in emotion regulation(Baseline, 6 weeks)

Study Sites (1)

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