Effect of cyclic versus continuous enteral nutrition on circadian rhythms in critical illness: the CIRCLES study - CIRCLES

eids Universitair Medisch Centrum0 个研究点目标入组 60 人开始时间: 待定最近更新: 2024年7月22日

适应症

试验速览

暂无简介。

•Receiving parenteral nutrition
•Oral intake
•Prior night-time (20.00h - 8.00h) enteral or parenteral nutrition within the
•same hospitalization before study inclusion
•Readmission to ICU with prior study inclusion
•Chronic enteral tube feeding prior to current admission
•Presence of one or more contraindications of enteral feeding and/or at
•significant risk for gastrointestinal tolerance according to standard protocol
•(including but not limited to gastrointestinal haemorrhage, intestinal ischemia
•or necrosis, impaired digestive tract integrity due to obstruction or
•perforation, gastrectomy, enterectomy, history of gastroparesis or oesophageal
•dysmotility or expected surgery within 24 hours)
•Patients with glycaemic emergency (including but not limited to
•hyperglycaemic hyperosmolar nonketotic coma, diabetic ketoacidosis, severe
•hypoglycaemia resulting in ICU admission) or patients controlling their glucose
•levels and insulin dosing via continuous glucose monitoring
•Treatment with extracorporeal membrane oxygenation
•Severe neurological damage (significant neurological abnormalities such as
•bleeding, ischemia, neurotrauma or severe encephalopathy with Glasgow Coma
•Scale <= 8)
•Suspected or confirmed pregnancy

发起方