Exploring the Efficacy of Ketamine Versus Fentanyl in Pain Management for Limb Injuries: A Randomized Controlled Trial
Phase 4
- Conditions
- Health Condition 1: T149- Unspecified injuryHealth Condition 2: T07- Unspecified multiple injuries
- Registration Number
- CTRI/2024/02/062489
- Lead Sponsor
- All India Institute of Medical SciencesAIIMSJodhpur
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
STUDY GROUP: Patients presenting to AIIMS emergency department with isolated Limb
injuries
INCLUSION CRITERIA:
Age – 18-70 yrs with Moderate and Severe pain (VAS =4) and systolic blood pressure
(SBP) of 90-180 mm of Hg
Exclusion Criteria
EXCLUSION CRITERIA:
1. Threatened Airway
2. Chest injury
3. Neurovascular deficiency
4. Grade 3 and Grade 4 shock
5. Pregnancy
6. History of allergy to ketamine, fentanyl (or opioids)
7. History of liver disease
8. History of renal disease
9. History of heart disease
10.History of psychiatric illness
11.Inability to understand the VAS pain rating system
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The Primary outcome measure of the study is decrease in the VAS score in the two <br/ ><br>groups (One group that received Ketamine & the other that received Fentanyl).Timepoint: 18 months
- Secondary Outcome Measures
Name Time Method Secondary Objectives <br/ ><br>1. Proportion of patients who need additional Rescue Medications for pain <br/ ><br>2. Proportion of patients who need Rescue Medications for pain during minor <br/ ><br>procedures <br/ ><br>3. Adverse reactions in the two groupsTimepoint: 18 months