Spectroscopic Evaluation of Middle Ear Infection
试验速览
- 阶段
- 不适用
- 状态
- 撤回
- 主要终点
- Middle Ear exam
研究概览
简要总结
Otitis media is more common in young children and it is estimated that 75% of all children experience at least one episode before the age of three. Otitis media is one of the common pediatric diagnoses and recurrent episodes account for the most commonly performed surgical procedure. Despite this a high degree of inaccuracy exists in diagnosis of this condition which depends on subjective assessment of the ear drum via direct visualization using an otoscope. Researcher can use Diffuse optical spectroscopy and diffuse optical imaging for the analysis of ear drum and the middle ear.
详细描述
The research can use low energy laser signal light from Diffuse optical spectroscopy that is harmless to the tissues and sends them into the ear canal to measure the tissue optical properties including the absorption of the laser signal and the amount of signal that will be backscattered by the ear drum. These measurements will then be analyzed using a microprocessor to determine presence of fluid or inflammation of the eardrum.
Diffuse optical spectroscopy an imaging method use near- infrared light to measure absolute tissue concentrations of oxyhemoglobin, deoxyhemoglobin, water, and lipids, as well as subtle changes in water and protein binding states
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Cross Sectional
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Male/ female at all age- newborn to adult.
- •Non- pregnant woman.
- •Diagnose of middle ear infection and plan for surgery procedure.
排除标准
- •Pregnant woman
- •Incompetent adults (i.e. individuals with cognitive impairment)
- •No diagnose of middle ear infection and no plan for surgery procedure.
- •Adults with cognitive impairment and children of parents that are cognitively impaired and thus are unable to consent will be excluded from the study.
结局指标
主要结局
Middle Ear exam
时间窗: 6 hours
Diffuse optical spectroscopy imaging to evaluate ear drum
次要结局
未报告次要终点
研究者
Beckman Laser Institute and Medical Center
Elliot Botvinick, Ph.D., Assistant Professor, Biomedical Engineering
University of California, Irvine