EUCTR2015-003362-84-ES进行中（未招募）1 期
Phase Ib clinical trial on the safety of immunotherapy with autologous dendritic cells primed with lysate allogeneic tumor lines in patients with diffuse intrinsic pontine glioma ( DIPG )
适应症
试验速览
- 阶段
- 1 期
- 状态
- 进行中（未招募）
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional clinical trial of medicinal product
入排标准
- 性别
- All
入选标准
- •Newly diagnosed DIPG
- •Patients without progressive disease
- •Aged between 3 and 18 yo
- •Lansky scale >50 (Karnosfsky for patients aged more than 16 yr)
- •Life expectancy > 8 weeks
- •Preserved bone marrow function
- •Normal hepatic and renal function
- •Are the trial subjects under 18? yes
- •Number of subjects for this age range: 10
- •F.1.2 Adults (18-64 years) no
- •F.1.2.1 Number of subjects for this age range
- •F.1.3 Elderly (>=65 years) no
- •F.1.3.1 Number of subjects for this age range
排除标准
- •Impossibility to perform aphaeresis
- •Patient part of other experimental study within the last 3 months
- •Patient under antitumor treatment in the last 4 weeks
- •Co-morbidity that does not allow the study treatment
- •Patients requiring > 2mg/day of dexametasone treatment
- •Corticoid-dependent patients
- •Patients under uncontrolled infection
- •Positive serologies of HIV, HCV or HBV
研究者
相似试验
尚未招募
1 期
A Vaccine for preventing PregnancyCTRI/2017/09/009934Indian Council of Medical Research
已完成
不适用
Phase I clinical trial to assess safety and immunogenicity of an MVA-based influenza H5 vaccine in healthy adultsflu10047438InfluenzaNL-OMON38408Erasmus MC, Universitair Medisch Centrum Rotterdam27
进行中（未招募）
1 期
Safety and immunogenicity of RNA-based vaccines against SARS-CoV-2 variants in healthy participantsProtection against Severe Acute Respiratory Syndrome Coronavirus 2 (SARS CoV 2).MedDRA version: 23.0Level: PTClassification code 10051905Term: Coronavirus infectionSystem Organ Class: 10021881 - Infections and infestationsMedDRA version: 23.0Level: HLTClassification code 10084510Term: Coronavirus infectionsSystem Organ Class: 10021881 - Infections and infestationsMedDRA version: 23.1Level: LLTClassification code 10084529Term: 2019 novel coronavirus infectionSystem Organ Class: 10021881 - Infections and infestationsEUCTR2021-003458-22-DEBioNTech SE1,470
招募中
1 期
evaluate the safety and immunomodulatory efficacy of Byolic CC supplementImmunomodulatory effect on healthy volunteers.IRCT20240304061158N4Behpad Teb Iranian90
进行中（未招募）
不适用
Phase I and IIa trial to assess the safety, immunogenicity and protective efficacy against sporozoite challenge of the candidate malaria vaccine pfLSA-3 vaccine. - LSA3-trialP. falciparum infection (malaria)EUCTR2006-001743-66-NLINSTITUT PASTEUR, Biomedical Parasitology Unit