The Impact of Using Triclosan-antibacterial Sutures on the Incidence of Surgical Site Infection

Phase 4

Completed

• Conditions: Surgical Site Infection
• Interventions: Other: Vicryl Plus; Other: Vicryl

• Registration Number: NCT01019447
• Lead Sponsor: Cairo University

Brief Summary

To compare conventional polyglactin 910 sutures with triclosan-coated polyglactin 910 antimicrobial sutures for the reduction of surgical site infections and any associated health and economic benefits.

Detailed Description

Not available

Study Timeline

• Status Verified: 2009-11
• Study Start: 2009-11
• Study First Submitted: 2009-11-23
• Study First Submitted QC: 2009-11-23
• Study First Posted: 2009-11-25
• Primary Completion: 2011-03
• Study Completion: 2011-03
• Last Update Submitted: 2011-06-21
• Last Update Posted: 2011-06-22

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 701

Inclusion Criteria

• All patients of different age
• Gender
• Risk factors and procedures candidate for surgical intervention during the period of the study

Exclusion Criteria

• Patients with an established pre-operative infection at the operative site

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Study group	Vicryl Plus	The study group in which Triclosan-coated polyglactin 910 antimicrobial sutures will be used.
Control group	Vicryl	The control group in which polyglactin 910 antimicrobial sutures will be used.

Primary Outcome Measures

Name	Time	Method
Signs of Surgical Site Infections (SSI) according to Centers for Disease Control (CDC) criteria	30 days (or 1 year in case of prosthesis)

Secondary Outcome Measures

Name	Time	Method
Post-operative hospital stay in days	30 days

Trial Locations

Locations (2)

Cairo University Kasr Al-Aini Hospital; 🇪🇬 Cairo, Egypt

Al-Zeraaein Hospital; 🇪🇬 Cairo, Egypt