rine TIMP2.IGFBP7 reflects kidney injury after moderate volume paracentesis in patients with ascites: A randomized control study
- Conditions
- - Acute tubular injury in cirrhotic patient who received abdominal paracentesis - Diuretic resistance or diuretic intractable ascites in cirrhotic patient- Cirrhosis with ascites- Diuretic resistance ascites- Acute tubular injury- Decompensated cirrhosis- Diuretic intractable ascites- Abdominal paracentesis
- Registration Number
- TCTR20191116003
- Brief Summary
rine TIMP2.IGFBP7 more than 2 predicted renal tubular injury in patients in the ascites release 5 L group therefore, ascites release 5 L may not be safe. Kidney injury could occur even less than 5 liters of ascites release in decompensated cirrhosis as demonstrated.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 30
Aged equal or more than 18 years old
- Cirrhosis with diuretic-resistance ascites or diuretic-intractable ascites
- Informed consent before enrollment
- Chronic kidney disease who received renal replacement therapy
- Acute kidney injury during enrollment
- Congestive heart failure and cardiac arrhythmia patient
- Patient with cardiac pacemaker devices
- Patient with shock
- Patient who have injected with contrast media within 2 weeks
- Active urinary tract infection
- Pregnancy
- Patient who have hemodynamic unstable from previous abdominal paracentesis
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Acute tubular injury in cirrhosis who received abdominal paracentesis Before and after abdominal paracentesis Change of urine TIMP-2.IGFBP-7 In urine
- Secondary Outcome Measures
Name Time Method CKD progression, mortality in 90 days, Readmission 90 days Decline in GFR, Death and admission times