The efficacy of intratympanic injection of nanogel dexamethasone in Sudden Sensorineural Hearing Loss (SSNHL) treatment,

Phase 3

Conditions: Sudden Sensorineural Hearing Loss.
Sudden idiopathic hearing loss, unspecified ear
H91.20

Registration Number: IRCT20220307054210N1

Lead Sponsor: Kerman University of Medical Sciences

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Complete

Sex: All

Target Recruitment: 90

Inclusion Criteria

One-way SSNHL at 30 dB at three consecutive frequencies generated in 72 hours or less
The time period from the time of hearing loss until the patient is admitted to the hospital for the procedure is less than or equal to 45 days

Exclusion Criteria

Evidence of otitis media on examination and history
Known history of ear anomaleis
Evidence of retrocuclear disease,
history of meniere's disease
history of acoustic trauma
history of immunodeficiency
history of sudden sensory neural hearing loss with other known couses
history of heart disease

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Hearing level. Timepoint: Measurement of the patient's hearing level at the beginning of the study (before the intervention) and 2 weeks after and 2 months after the start of the treatment period. Method of measurement: The hearing level was measured with audiometric criteria (PTA and srt) using an audiogram.;Vertigo. Timepoint: Vertigo was examined before the start of treatment and 2 weeks and 2 months after the start of treatment. Method of measurement: Dizziness was investigated using a questionnaire.;Tinnitus. Timepoint: tinnitus was examined before the start of treatment and 2 weeks and 2 months after the start of treatment. Method of measurement: tinnitus was investigated using a questionnaire.

Secondary Outcome Measures

Name	Time	Method
SRT :(speech recognition threshold). Timepoint: before intervention and 2 and 4 weeks after intervention. Method of measurement: audiometry.;PTA:( pure tone audiometry). Timepoint: before intervention and 2 and 4 weeks after intervention. Method of measurement: audiometry.