NCT00648310已完成2 期
Is There A Synergic Effect Of Topical Oestrogens When Associated To Antimuscarinics In The Treatment Of Symptomatic Detrusor Overactivity
Università degli Studi dell'Insubria1 个研究点 分布在 1 个国家开始时间: 2004年1月最近更新:
适应症
干预措施
相关药物
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 发起方
- 试验地点
- 1
研究概览
简要总结
Despite the great number of reports about the efficacy of oestrogens or antimuscarinics on OAB symptoms, so far no author has tried to investigate whether the concomitant administration of these two drugs, acting on two different pathophysiological mechanisms, could have a synergic effect reducing the rate of non-responders to treatment.
研究设计
- 研究类型
- Interventional
入排标准
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •All post-menopausal women with symptoms of overactive bladder and urodynamically proven pure detrusor overactivity
排除标准
- •concomitant urodynamic stress incontinence
- •documented recurrent urinary tract infections
- •previous antimuscarinic treatment
- •previous pelvic surgery
- •concomitant systemic HRT
- •history of breast or endometrial cancer
- •neurological disease
- •clinical contraindications to treatment with oestrogen or antimuscarinics
- •patients included in other ongoing clinical trials
研究组 & 干预措施
1
Active Comparator
arm 1: Tolterodine 4 mg once daily for 12 weeks
干预措施: Tolterodine 4 mg (Drug)
研究者
研究点 (1)
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