Comprehensive ascertainment of bleeding in patients prescribed different combinations of dual antiplatelet therapy (DAPT) and triple therapy (TT, DAPT plus an anticoagulant) after coronary interventions in the UK: a population based cohort study (the ADAPTT study)

niversity of Bristol (UK)0 个研究点目标入组 21,961 人开始时间: 2016年2月19日最近更新: 2023年7月25日

适应症

试验速览

2022 Results article in https://pubmed.ncbi.nlm.nih.gov/35961692/ Patients with acute coronary syndrome (ACS) undergoing percutaneous coronary intervention (PCI) (added 15/08/2022) 2023 Results article in https://doi.org/10.3310/mnjy9014 (added 13/07/2023)

•Patients will be included if they:
•1. Are labelled as ‘acceptable’ for use in research by CPRD (a process that identifies and excludes patients with non-continuous follow up or patients with poor data recording that raises suspicion as to the validity of that patient’s record)
•2. Are over 18 years of age
•3. Have one year of medical history in CPRD before cohort entry (time of index procedure or event)
•4. Have a record of aspirin monotherapy (Asp) or dual antiplatelet therapy (DAPT: aspirin and clopidogrel, AC; aspirin and prasugrel, AP; aspirin and ticagrelor, AT) in the year following the index procedure or event
•5. No record of DAPT in the 3 month prior to the index procedure or event

发起方

niversity of Bristol (UK)