Evaluating the effects of local endometrial injury on success of pregnancy rate in patients candidate for in vitro fertilization.
Not Applicable
Recruiting
- Conditions
- Infertility.Female infertility
- Registration Number
- IRCT20140224016705N11
- Lead Sponsor
- Shahid Beheshti University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Female
- Target Recruitment
- 324
Inclusion Criteria
History of infertility with a history of unsuccessful IVF
candidate for in vitro fertilization
Existence of inappropriate endometrial thickness based on ultrasound
Age 40 years or less
Do not use OCP or GnRH for FET in the previous cycle
Appropriate quality of embryos for transfer
Exclusion Criteria
Vaginal or cervical active infection
Endometrial Hyperplasia
Existence of endometritis
Presence of known intrauterine pathologies on ultrasound or hysteroscopy such as fibroids or myomas
Asherman syndrome
Uterine anomaly
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Existence of clinical pregnancy (formation of pregnancy sac and fetal heart) in IVF patient under the intervention of endometrial abrasion with papillae. Timepoint: 5 weeks after the transfer, transvaginal ultrasound will examine the presence of clinical pregnancy (formation of pregnancy sac and fetal heart). Method of measurement: transvaginal ultrasound.;ß-hCG positivity (greater than 10 mIU / mL). Timepoint: ?-hCG titer was checked 2 weeks after embryo transfer. Method of measurement: Using a laboratory-approved ß-hCG test.;The effect of endometrial abrasion on endometrial condition. Timepoint: On day 8-10 of the cycle, an ultrasound will be performed again and the condition of the endometrium will be examined. Method of measurement: transvaginal ultrasound.
- Secondary Outcome Measures
Name Time Method