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Clinical Trials/NCT05179382
NCT05179382
Completed
Not Applicable

Integrated Analysis of Autonomic, Cardiovascular and Respiratory Parameters in Recovery After Physical Exercise With and Without Water Ingestion: Crossover Non-randomized Clinical Test

Luiz Carlos Marques Vanderlei1 site in 1 country54 target enrollmentJanuary 1, 2022
ConditionsHealthy

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Healthy
Sponsor
Luiz Carlos Marques Vanderlei
Enrollment
54
Locations
1
Primary Endpoint
Autonomic Modulation - SD1 index
Status
Completed
Last Updated
2 years ago

Overview

Brief Summary

This study aims to evaluate post-exercise recovery in healthy young men submitted to a prolonged exercise protocol of submaximal intensity with or without water intake, from the integrated analysis of autonomic (heart rate variability indices), cardiovascular outcomes (systolic blood pressure, diastolic blood pressure and heart rate) and respiratory (oxygen saturation and respiratory frequency). In addition, it will also be evaluated whether the proposed model is able to estimate the number of individuals undergoing hydration that have better recovery.

Registry
clinicaltrials.gov
Start Date
January 1, 2022
End Date
July 6, 2022
Last Updated
2 years ago
Study Type
Interventional
Study Design
Crossover
Sex
Male

Investigators

Sponsor
Luiz Carlos Marques Vanderlei
Responsible Party
Sponsor Investigator
Principal Investigator

Luiz Carlos Marques Vanderlei

PhD

Universidade Estadual Paulista Júlio de Mesquita Filho

Eligibility Criteria

Inclusion Criteria

  • Include healthy and male individuals, age between 18 and 25 years and physically active.

Exclusion Criteria

  • Volunteers with at least one of the following characteristics will be excluded: smoking, use of drugs that influence the autonomic activity of the heart, alcoholics, people with known metabolic and/or endocrine disorders, and sedentary individuals, insufficiently active and very active.

Outcomes

Primary Outcomes

Autonomic Modulation - SD1 index

Time Frame: Acute evaluation during interventions

he data for this evaluation will be collected using a heart rate monitor that registers the heart rate beat by beat and provides information regarding the RR intervals. The SD1 index corresponds to the dispersion of points perpendicular to the line of identity of the ellipse obtained from the Poincaré plot. Expressed in milliseconds.

Blood Pressure

Time Frame: Acute evaluation during interventions

Will occur indirectly, using a stethoscope and an aneroid sphygmomanometer in the left arm. The indicated values will be registered in an individual form. To avoid errors in the determination of blood pressures in volunteers, a single evaluator will measure these variables throughout the experimental procedure. Data will be collected at the end of the 10 minutes of initial rest and at minutes 30, 60 and 90 during exercise on the treadmill, as well as will be collected at minutes 1, 3, 5, 7, 10, 20, 30, 40, 50 and 60 of recovery.

Peripheral oxygen saturation

Time Frame: Acute evaluation during interventions

Will be checked using a pulse oximeter. A pulse oximeter is a device that provides blood saturation readings, evaluating the absorption behavior of oxyhemoglobin and deoxyhemoglobin in relation to the lengths of red and infrared light. Data will be collected at the end of the 10 minutes of initial rest and at minutes 30, 60 and 90 during exercise on the treadmill, as well as will be collected at minutes 1, 3, 5, 7, 10, 20, 30, 40, 50 and 60 of recovery.

Autonomic Modulation - HF index

Time Frame: Acute evaluation during interventions

he data for this evaluation will be collected using a heart rate monitor that registers the heart rate beat by beat and provides information regarding the RR intervals. The HF index is the high-frequency component of the oscillatory components of heart rate variability, and ranges from 0.15 to 0.4 Hz.

Autonomic Modulation - SDNN index

Time Frame: Acute evaluation during interventions

The data for this evaluation will be collected using a heart rate monitor that registers the heart rate beat by beat and provides information regarding the RR intervals. The SDNN index corresponds to the standard deviation of all normal RR intervals recorded in a time interval, expressed in milliseconds.

Heart Rate

Time Frame: Acute evaluation during interventions

The heart rate will be captured beat by beat using the Polar RS800CX frequency meter, equipment previously validated to capture this parameter. Data will be collected at the end of the 10 minutes of initial rest and at minutes 30, 60 and 90 during exercise on the treadmill, as well as will be collected at minutes 1, 3, 5, 7, 10, 20, 30, 40, 50 and 60 of recovery.

Autonomic Modulation - rMSSD index

Time Frame: Acute evaluation during interventions

The data for this evaluation will be collected using a heart rate monitor that registers the heart rate beat by beat and provides information regarding the RR intervals. The rMSSD index corresponds to the root-mean square of differences between adjacent normal RR intervals in a time interval, expressed in milliseconds.

Autonomic Modulation - LF index

Time Frame: Acute evaluation during interventions

The data for this evaluation will be collected using a heart rate monitor that registers the heart rate beat by beat and provides information regarding the RR intervals. The LF index is the low-frequency component of the oscillatory components of heart rate variability, and ranges from 0.04 to 0.15 Hz.

Respiratory Rate

Time Frame: Acute evaluation during interventions

The measurements will be performed by counting the breaths for one minute without the volunteer being aware of the process, so that the usual breathing characteristics are not modified. Data will be collected at the end of the 10 minutes of initial rest as well as will be collected at minutes 1, 3, 5, 7, 10, 20, 30, 40, 50 and 60 of recovery.

Autonomic Modulation - SD2 index

Time Frame: Acute evaluation during interventions

The data for this evaluation will be collected using a heart rate monitor that registers the heart rate beat by beat and provides information regarding the RR intervals. The SD2 index corresponds to the dispersion of points along the line of identity of the ellipse obtained from the Poincaré plot. Expressed in milliseconds.

Study Sites (1)

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